Antiviral effect in human cytomegalovirus-infected cells, pharmacokinetics, and intravitreal toxicology in rabbits of acyclovir diphosphate dimyristoylglycerol

• Published in: Antimicrobial Agents and Chemotherapy 1995-06, Vol.39 (6), p.1383-1385
• Main Authors: SHAKIBA, S, FREEMAN, W. R, GARDNER, M. F, HOSTETLER, K. Y, FLORES-AGUILAR, M, MUNGUIA, D, TATEBAYASHI, M, BESEN, G, AMANI, R, WILEY, C. A, CHOU VUONG, ALDERN, K. A
• Format: Article
• Language: English
• Subjects: Acyclovir; Acyclovir - analogs & derivatives; Acyclovir - pharmacokinetics; Acyclovir - pharmacology; Acyclovir - toxicity; Animals; Antibiotics. Antiinfectious agents. Antiparasitic agents; Antiviral Agents; Antiviral Agents - pharmacokinetics; Antiviral Agents - pharmacology; Antiviral Agents - toxicity; Biological and medical sciences; Cells, Cultured; Comparative Study; Cytomegalovirus - drug effects; Drug Carriers; Ganciclovir - pharmacokinetics; Humans; Liposomes; Medical sciences; Pharmacology. Drug treatments; Phosphatidylglycerols; Phosphatidylglycerols - pharmacokinetics; Phosphatidylglycerols - pharmacology; Phosphatidylglycerols - toxicity; Prodrugs; Prodrugs - pharmacokinetics; Prodrugs - pharmacology; Prodrugs - toxicity; Rabbits; Research Support, U.S. Gov't, Non-P.H.S; Research Support, U.S. Gov't, P.H.S; Virus Replication - drug effects; Vitreous Body; Vitreous Body - metabolism
• ISSN: 0066-4804; 1098-6596
• DOI: 10.1128/AAC.39.6.1383

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