Diagnostic and prognostic value of fibrin stabilising factor in Schönlein-Henoch syndrome

Fibrin stabilising factor (FSF) was studied in the circulating blood of 196 children. These 196 children comprised three groups: 131 controls (group A), 20 children with diseases of potential repercussion on FSF determination (group B), and 45 children with Schönlein-Henoch syndrome (group C). Deter...

Full description

Saved in:
Bibliographic Details
Published in:Archives of disease in childhood 1983-01, Vol.58 (1), p.12-14
Main Authors: Dalens, B, Travade, P, Labbé, A, Bezou, M J
Format: Article
Language:English
Subjects:
Child
Factor XIII - analysis
Fibrinogen - analysis
Humans
Kidney Diseases - complications
Prognosis
Prospective Studies
Purpura, Schoenlein-Henoch - blood
Purpura, Schoenlein-Henoch - complications
Purpura, Schoenlein-Henoch - diagnosis
Risk assessment
Citations: Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Fibrin stabilising factor (FSF) was studied in the circulating blood of 196 children. These 196 children comprised three groups: 131 controls (group A), 20 children with diseases of potential repercussion on FSF determination (group B), and 45 children with Schönlein-Henoch syndrome (group C). Determinations from groups A and B produced normal values, but results from group C were significantly lower at the onset of the vasculitis. Seventeen children with Schönlein-Henoch syndrome have had complications, in 7 of whom these were severe. The decrease in FSF levels was correlated with the severity of such complications, and an increase in FSF was associated with recovery. Determination of FSF activity appears to help in the diagnosis of Schönlein-Henoch vasculitis, as well as helping to monitor the course of the disease and assessing the risks of complications.
ISSN:0003-9888
1468-2044
DOI:10.1136/adc.58.1.12