Cystic fibrosis and coeliac disease: coexistence in two children

Two children, unrelated, in whom cystic fibrosis had been diagnosed at the ages of 14 weeks and 10 months, respectively, were found subsequently to suffer from coeliac disease as well. Both children are responding well to dietary gluten withdrawal and to conventional treatment for cystic fibrosis. I...

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Bibliographic Details
Published in:Archives of disease in childhood 1973-09, Vol.48 (9), p.684-691
Main Authors: Goodchild, M C, Nelson, R, Anderson, C M
Format: Article
Language:English
Subjects:
Biopsy
Body Height
Body Weight
Celiac Disease - complications
Celiac Disease - therapy
Child
Child, Preschool
Chlorides - analysis
Cystic Fibrosis - complications
Cystic Fibrosis - drug therapy
Cystic Fibrosis - therapy
Diet Therapy
Feeding and Eating Disorders - etiology
Female
Glutens
Humans
Infant
Iron - therapeutic use
Jejunum - pathology
Original
Prednisolone - therapeutic use
Sodium - analysis
Sweat - analysis
Vomiting - etiology
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Summary:Two children, unrelated, in whom cystic fibrosis had been diagnosed at the ages of 14 weeks and 10 months, respectively, were found subsequently to suffer from coeliac disease as well. Both children are responding well to dietary gluten withdrawal and to conventional treatment for cystic fibrosis. It is suggested that cystic fibrosis may predispose to the development of coeliac disease. Therefore, jejunal biopsy may be a useful investigation in the occasional child with cystic fibrosis, who presents with unusual features, and who fails to thrive as well as expected.
ISSN:0003-9888
1468-2044
DOI:10.1136/adc.48.9.684