Sister chromatid exchange frequencies in Progeria and Werner syndrome patients

An analysis of the baseline and mitomycin-C-induced sister chromatid exchange (SCE) frequencies in peripheral lymphocytes derived from three patients with progeria and three Werner syndrome patients is presented. SCE frequencies did not differ significantly between the two groups of patients and the...

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Bibliographic Details
Published in:American journal of human genetics 1981-09, Vol.33 (5), p.762-766
Main Authors: Darlington, G J, Dutkowski, R, Brown, W T
Format: Article
Language:English
Subjects:
Adult
Bromodeoxyuridine - pharmacology
Crossing Over, Genetic - drug effects
Female
Humans
Male
Metaphase
Mitomycins - pharmacology
Progeria - genetics
Sister Chromatid Exchange - drug effects
Werner Syndrome - genetics
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Summary:An analysis of the baseline and mitomycin-C-induced sister chromatid exchange (SCE) frequencies in peripheral lymphocytes derived from three patients with progeria and three Werner syndrome patients is presented. SCE frequencies did not differ significantly between the two groups of patients and their normal controls.
ISSN:0002-9297
1537-6605