Aryl hydrocarbon hydroxylase in cultured lymphocytes of twins

Measurement of aryl hydrocarbon hydroxylase (AHH) in cultured lymphocytes of 18 monozygotic and 30 dizygotic twin pairs showed that basal and induced AHH activity and AHH inducibility are heritable traits. The data are consistent with AHH inducibility being determined by a single or a very few polym...

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Bibliographic Details
Published in:American journal of human genetics 1978-09, Vol.30 (5), p.561-571
Main Authors: Paigen, B, Ward, E, Steenland, K, Houten, L, Gurtoo, H L, Minowada, J
Format: Article
Language:English
Subjects:
Aryl Hydrocarbon Hydroxylases - biosynthesis
Aryl Hydrocarbon Hydroxylases - metabolism
Cells, Cultured
Enzyme Induction
Female
Genes
Humans
Lymphocytes - enzymology
Male
Pregnancy
Twins
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Summary:Measurement of aryl hydrocarbon hydroxylase (AHH) in cultured lymphocytes of 18 monozygotic and 30 dizygotic twin pairs showed that basal and induced AHH activity and AHH inducibility are heritable traits. The data are consistent with AHH inducibility being determined by a single or a very few polymorphic genes.
ISSN:0002-9297
1537-6605