Immunoconglutinin levels in normal and diseased population groups in Southern Africa

Immunoconglutinin (I-K) levels were measured in adult blood donors of European and African origin and in patients with the following diseases: acute typhoid fever, amoebic liver abscess, chronic liver disease and primary hepatoma. The lowest levels were found in the white donor group and the highest...

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Bibliographic Details
Published in:Clinical and experimental immunology 1971-06, Vol.8 (6), p.871-880
Main Author: Watson, K C
Format: Article
Language:English
Subjects:
Adolescent
Adult
African Continental Ancestry Group
Aged
Antibodies - analysis
Autoantibodies - analysis
Carcinoma, Hepatocellular - immunology
Child
Child, Preschool
Chronic Disease
European Continental Ancestry Group
gamma-Globulins - analysis
Humans
Immunoglobulin A - analysis
Immunoglobulin G - analysis
Immunoglobulin M - analysis
Liver Abscess, Amebic - immunology
Liver Diseases - immunology
Liver Neoplasms - immunology
Middle Aged
Typhoid Fever - immunology
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Summary:Immunoconglutinin (I-K) levels were measured in adult blood donors of European and African origin and in patients with the following diseases: acute typhoid fever, amoebic liver abscess, chronic liver disease and primary hepatoma. The lowest levels were found in the white donor group and the highest in those with chronic liver disease and those with primary hepatoma. African donors had levels higher than white donors which may relate to chronic infection and particularly chronic parasitic infestation. There was poor correlation between `O' and `H' antibodies and I-K levels in the typhoid group. In those with chronic liver disease there was some correlation between I-K levels and total γ-globulin and also with raised IgM and IgA levels but not with raised IgG.
ISSN:0009-9104
1365-2249