Heterogeneity of atypical haemolytic uraemic syndromes

Atypical, non-diarrhoea associated haemolytic uraemic syndrome (D−HUS) is a heterogeneous disorder with a generally poor outcome, although this view has now been questioned. The clinical and laboratory features of 23 children with D−HUS, representing a third of all patients with HUS seen during the...

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Bibliographic Details
Published in:Archives of disease in childhood 1997-06, Vol.76 (6), p.518-521
Main Authors: Neuhaus, Thomas J, Calonder, Seraina, Leumann, Ernst P
Format: Article
Language:English
Subjects:
Acute Disease
Adolescent
Age
Anemias. Hemoglobinopathies
Attrition (Research Studies)
Biological and medical sciences
Blood pressure
Body Weight
Cardiomyopathy
Child
Child, Preschool
Dialysis
Diarrhea - etiology
Diseases of red blood cells
Epidemiology
Female
Follow-Up Studies
haemolytic uraemic syndromes
Hematologic and hematopoietic diseases
Hemolytic-Uremic Syndrome - complications
Hemolytic-Uremic Syndrome - diagnosis
Hemolytic-Uremic Syndrome - therapy
Heterogeneity
Humans
Hypertension
Infant
Infant, Newborn
Infants
Infections
Kidney Failure, Chronic - etiology
Long term
Male
Medical sciences
Minicourses
Mortality
Narcotics
Neonates
Original
Patients
Peritoneal dialysis
Plasma
Prognosis
Recurrence
Renal Dialysis
Statistical Analysis
Urine
Young Children
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Summary:Atypical, non-diarrhoea associated haemolytic uraemic syndrome (D−HUS) is a heterogeneous disorder with a generally poor outcome, although this view has now been questioned. The clinical and laboratory features of 23 children with D−HUS, representing a third of all patients with HUS seen during the last 26 years, were examined. The median age was 4.9 years (range 3 days–13.8 years). Twenty one children (91%) survived the initial phase. All patients except six infants aged
ISSN:0003-9888
1468-2044
DOI:10.1136/adc.76.6.518