Longitudinal relation between limited joint mobility, height, insulin-like growth factor 1 levels, and risk of developing microalbuminuria: the Oxford Regional Prospective Study

• Published in: Archives of disease in childhood 2005-10, Vol.90 (10), p.1039-1044
• Main Authors: Amin, R, Bahu, T K, Widmer, B, Dalton, R N, Dunger, D B
• Format: Article
• Language: English
• Subjects: ACR; Adolescent; Adult; albumin:creatinine ratio; Albuminuria; Albuminuria - blood; Albuminuria - etiology; Albuminuria - physiopathology; Analysis; Biological and medical sciences; blood pressure; Body Height; Child; Child, Preschool; coefficient of variation; Creatinine; Development and progression; Diabetes; Diabetes Mellitus, Type 1 - blood; Diabetes Mellitus, Type 1 - complications; Diabetes Mellitus, Type 1 - physiopathology; Diagnosis; Female; Finger Joint - physiopathology; General aspects; Glycated Hemoglobin A - analysis; growth hormone; Humans; IGF-1; Infant; Insulin; Insulin-like growth factor 1; Insulin-like growth factor I; Insulin-Like Growth Factor I - analysis; Insulin-like growth factors; limited joint mobility; LJM; Longitudinal studies; Male; Medical sciences; Methods; microalbuminuria; Miscellaneous; Movement; Nephrology. Urinary tract diseases; Original; ORPS; Oxford Regional Prospective Study; Prevention and actions; Prognosis; Proportional Hazards Models; Prospective Studies; Puberty; Public health. Hygiene; Public health. Hygiene-occupational medicine; Risk Factors; SDS; standard deviation score; stature; T1DM; Type 1 diabetes; type 1 diabetes mellitus; Urinary system involvement in other diseases. Miscellaneous; Urinary tract. Prostate gland; Urine
• ISSN: 0003-9888; 1468-2044
• DOI: 10.1136/adc.2004.067272

Aims: To determine risk factors for development of microalbuminuria (MA) in relation to detection of limited joint mobility (LJM+) of the interphalangeal joints in a longitudinal cohort of type 1 diabetic (T1DM) subjects. Methods: A total of 479 T1DM subjects diagnosed