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Prenatal drug exposure and maternal and infant feeding behaviour

Objective: To evaluate feeding difficulties and maternal behaviour during a feeding session with 1 month old infants prenatally exposed to cocaine and/or opiates. Methods: The study is part of the maternal lifestyle study, which recruited 11 811 subjects at four urban hospitals, then followed 1388 f...

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Published in:Archives of disease in childhood. Fetal and neonatal edition 2003-09, Vol.88 (5), p.F391-F399
Main Authors: LaGasse, L L, Messinger, D, Lester, B M, Seifer, R, Tronick, E Z, Bauer, C R, Shankaran, S, Bada, H S, Wright, L L, Smeriglio, V L, Finnegan, L P, Maza, P L, Liu, J
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container_end_page F399
container_issue 5
container_start_page F391
container_title Archives of disease in childhood. Fetal and neonatal edition
container_volume 88
creator LaGasse, L L
Messinger, D
Lester, B M
Seifer, R
Tronick, E Z
Bauer, C R
Shankaran, S
Bada, H S
Wright, L L
Smeriglio, V L
Finnegan, L P
Maza, P L
Liu, J
description Objective: To evaluate feeding difficulties and maternal behaviour during a feeding session with 1 month old infants prenatally exposed to cocaine and/or opiates. Methods: The study is part of the maternal lifestyle study, which recruited 11 811 subjects at four urban hospitals, then followed 1388 from 1 to 36 months of age. Exposure to cocaine and opiates was determined by maternal interview and meconium assay. At the 1 month clinic visit, biological mothers were videotaped while bottle feeding their infants. This sample included 364 exposed to cocaine, 45 exposed to opiates, 31 exposed to both drugs, and 588 matched comparison infants. Mothers were mostly black, high school educated, and on public assistance. Videotapes were coded without knowledge of exposure status for frequency, duration and quality of infant sucking, arousal, feeding problems, and maternal feeding activity and interaction. Results: No cocaine effects were found on infant feeding measures, but cocaine-using mothers were less flexible (6.29 v 6.50), less engaged (5.77 v 6.22), and had shorter feeding sessions (638 v 683 seconds). Opiate exposed infants showed prolonged sucking bursts (29 v 20 seconds), fewer pauses (1.6 v 2.2 per minute), more feeding problems (0.55 v 0.38), and increased arousal (2.59 v 2.39). Their mothers showed increased activity (30 v 22), independent of their infants’ feeding problems. Conclusions: Previous concerns about feeding behaviour in cocaine exposed infants may reflect the quality of the feeding interaction rather than infant feeding problems related to prenatal exposure. However, opiate exposed infants and their mothers both contributed to increased arousal and heightened feeding behaviour.
doi_str_mv 10.1136/fn.88.5.F391
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Methods: The study is part of the maternal lifestyle study, which recruited 11 811 subjects at four urban hospitals, then followed 1388 from 1 to 36 months of age. Exposure to cocaine and opiates was determined by maternal interview and meconium assay. At the 1 month clinic visit, biological mothers were videotaped while bottle feeding their infants. This sample included 364 exposed to cocaine, 45 exposed to opiates, 31 exposed to both drugs, and 588 matched comparison infants. Mothers were mostly black, high school educated, and on public assistance. Videotapes were coded without knowledge of exposure status for frequency, duration and quality of infant sucking, arousal, feeding problems, and maternal feeding activity and interaction. Results: No cocaine effects were found on infant feeding measures, but cocaine-using mothers were less flexible (6.29 v 6.50), less engaged (5.77 v 6.22), and had shorter feeding sessions (638 v 683 seconds). Opiate exposed infants showed prolonged sucking bursts (29 v 20 seconds), fewer pauses (1.6 v 2.2 per minute), more feeding problems (0.55 v 0.38), and increased arousal (2.59 v 2.39). Their mothers showed increased activity (30 v 22), independent of their infants’ feeding problems. Conclusions: Previous concerns about feeding behaviour in cocaine exposed infants may reflect the quality of the feeding interaction rather than infant feeding problems related to prenatal exposure. However, opiate exposed infants and their mothers both contributed to increased arousal and heightened feeding behaviour.</description><identifier>ISSN: 1359-2998</identifier><identifier>EISSN: 1468-2052</identifier><identifier>DOI: 10.1136/fn.88.5.F391</identifier><identifier>PMID: 12937043</identifier><language>eng</language><publisher>London: BMJ Publishing Group Ltd and Royal College of Paediatrics and Child Health</publisher><subject>Addictive behaviors ; Adult ; Age ; Alcohol ; Arousal - drug effects ; Babies ; Behavior ; Biological and medical sciences ; Birth weight ; Bottle Feeding - psychology ; Care and treatment ; Chi-Square Distribution ; Childrens health ; Chromatography ; Cocaine ; Cocaine abuse ; Cocaine-Related Disorders - psychology ; Colleges &amp; universities ; Confidentiality ; Consent ; Diseases ; Drug abuse ; Drug addictions ; Drug use ; drugs ; Enzymes ; feeding ; Feeding and Eating Disorders - psychology ; Feeding behavior ; Feeding Behavior - drug effects ; Female ; Fetus ; Follow-Up Studies ; Gestational Age ; Health aspects ; Humans ; Hypotheses ; Immunoassay ; Infant ; Infant Behavior - drug effects ; Infants ; Infants (Newborn) ; Infants (Premature) ; Longitudinal Studies ; Male ; Maternal Behavior ; maternal-infant interaction ; Medical sciences ; Metabolites ; Mother-Child Relations ; Mothers ; Narcotics ; opiate ; Opioid-Related Disorders - psychology ; Original ; Pregnancy ; Pregnancy Complications - psychology ; Prenatal Exposure Delayed Effects ; Prevention ; Probiotics ; Risk factors ; Sucking Behavior - drug effects ; Toxicology ; Videotape Recording</subject><ispartof>Archives of disease in childhood. 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Fetal and neonatal edition</title><addtitle>Arch Dis Child Fetal Neonatal Ed</addtitle><description>Objective: To evaluate feeding difficulties and maternal behaviour during a feeding session with 1 month old infants prenatally exposed to cocaine and/or opiates. Methods: The study is part of the maternal lifestyle study, which recruited 11 811 subjects at four urban hospitals, then followed 1388 from 1 to 36 months of age. Exposure to cocaine and opiates was determined by maternal interview and meconium assay. At the 1 month clinic visit, biological mothers were videotaped while bottle feeding their infants. This sample included 364 exposed to cocaine, 45 exposed to opiates, 31 exposed to both drugs, and 588 matched comparison infants. Mothers were mostly black, high school educated, and on public assistance. 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Messinger, D ; Lester, B M ; Seifer, R ; Tronick, E Z ; Bauer, C R ; Shankaran, S ; Bada, H S ; Wright, L L ; Smeriglio, V L ; Finnegan, L P ; Maza, P L ; Liu, J</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-b612t-eff81d8d44dd7430d654c15c79e5f7984713355acfdb5ac3e51ca4158d7bf5093</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2003</creationdate><topic>Addictive behaviors</topic><topic>Adult</topic><topic>Age</topic><topic>Alcohol</topic><topic>Arousal - drug effects</topic><topic>Babies</topic><topic>Behavior</topic><topic>Biological and medical sciences</topic><topic>Birth weight</topic><topic>Bottle Feeding - psychology</topic><topic>Care and treatment</topic><topic>Chi-Square Distribution</topic><topic>Childrens health</topic><topic>Chromatography</topic><topic>Cocaine</topic><topic>Cocaine abuse</topic><topic>Cocaine-Related Disorders - psychology</topic><topic>Colleges &amp; universities</topic><topic>Confidentiality</topic><topic>Consent</topic><topic>Diseases</topic><topic>Drug abuse</topic><topic>Drug addictions</topic><topic>Drug use</topic><topic>drugs</topic><topic>Enzymes</topic><topic>feeding</topic><topic>Feeding and Eating Disorders - psychology</topic><topic>Feeding behavior</topic><topic>Feeding Behavior - drug effects</topic><topic>Female</topic><topic>Fetus</topic><topic>Follow-Up Studies</topic><topic>Gestational Age</topic><topic>Health aspects</topic><topic>Humans</topic><topic>Hypotheses</topic><topic>Immunoassay</topic><topic>Infant</topic><topic>Infant Behavior - drug effects</topic><topic>Infants</topic><topic>Infants (Newborn)</topic><topic>Infants (Premature)</topic><topic>Longitudinal Studies</topic><topic>Male</topic><topic>Maternal Behavior</topic><topic>maternal-infant interaction</topic><topic>Medical sciences</topic><topic>Metabolites</topic><topic>Mother-Child Relations</topic><topic>Mothers</topic><topic>Narcotics</topic><topic>opiate</topic><topic>Opioid-Related Disorders - psychology</topic><topic>Original</topic><topic>Pregnancy</topic><topic>Pregnancy Complications - psychology</topic><topic>Prenatal Exposure Delayed Effects</topic><topic>Prevention</topic><topic>Probiotics</topic><topic>Risk factors</topic><topic>Sucking Behavior - drug effects</topic><topic>Toxicology</topic><topic>Videotape Recording</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>LaGasse, L L</creatorcontrib><creatorcontrib>Messinger, D</creatorcontrib><creatorcontrib>Lester, B M</creatorcontrib><creatorcontrib>Seifer, R</creatorcontrib><creatorcontrib>Tronick, E Z</creatorcontrib><creatorcontrib>Bauer, C R</creatorcontrib><creatorcontrib>Shankaran, S</creatorcontrib><creatorcontrib>Bada, H S</creatorcontrib><creatorcontrib>Wright, L L</creatorcontrib><creatorcontrib>Smeriglio, V L</creatorcontrib><creatorcontrib>Finnegan, L P</creatorcontrib><creatorcontrib>Maza, P L</creatorcontrib><creatorcontrib>Liu, J</creatorcontrib><collection>Istex</collection><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Health &amp; 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Fetal and neonatal edition</jtitle><addtitle>Arch Dis Child Fetal Neonatal Ed</addtitle><date>2003-09-01</date><risdate>2003</risdate><volume>88</volume><issue>5</issue><spage>F391</spage><epage>F399</epage><pages>F391-F399</pages><issn>1359-2998</issn><eissn>1468-2052</eissn><abstract>Objective: To evaluate feeding difficulties and maternal behaviour during a feeding session with 1 month old infants prenatally exposed to cocaine and/or opiates. Methods: The study is part of the maternal lifestyle study, which recruited 11 811 subjects at four urban hospitals, then followed 1388 from 1 to 36 months of age. Exposure to cocaine and opiates was determined by maternal interview and meconium assay. At the 1 month clinic visit, biological mothers were videotaped while bottle feeding their infants. This sample included 364 exposed to cocaine, 45 exposed to opiates, 31 exposed to both drugs, and 588 matched comparison infants. Mothers were mostly black, high school educated, and on public assistance. Videotapes were coded without knowledge of exposure status for frequency, duration and quality of infant sucking, arousal, feeding problems, and maternal feeding activity and interaction. Results: No cocaine effects were found on infant feeding measures, but cocaine-using mothers were less flexible (6.29 v 6.50), less engaged (5.77 v 6.22), and had shorter feeding sessions (638 v 683 seconds). Opiate exposed infants showed prolonged sucking bursts (29 v 20 seconds), fewer pauses (1.6 v 2.2 per minute), more feeding problems (0.55 v 0.38), and increased arousal (2.59 v 2.39). Their mothers showed increased activity (30 v 22), independent of their infants’ feeding problems. Conclusions: Previous concerns about feeding behaviour in cocaine exposed infants may reflect the quality of the feeding interaction rather than infant feeding problems related to prenatal exposure. 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subjects Addictive behaviors
Adult
Age
Alcohol
Arousal - drug effects
Babies
Behavior
Biological and medical sciences
Birth weight
Bottle Feeding - psychology
Care and treatment
Chi-Square Distribution
Childrens health
Chromatography
Cocaine
Cocaine abuse
Cocaine-Related Disorders - psychology
Colleges & universities
Confidentiality
Consent
Diseases
Drug abuse
Drug addictions
Drug use
drugs
Enzymes
feeding
Feeding and Eating Disorders - psychology
Feeding behavior
Feeding Behavior - drug effects
Female
Fetus
Follow-Up Studies
Gestational Age
Health aspects
Humans
Hypotheses
Immunoassay
Infant
Infant Behavior - drug effects
Infants
Infants (Newborn)
Infants (Premature)
Longitudinal Studies
Male
Maternal Behavior
maternal-infant interaction
Medical sciences
Metabolites
Mother-Child Relations
Mothers
Narcotics
opiate
Opioid-Related Disorders - psychology
Original
Pregnancy
Pregnancy Complications - psychology
Prenatal Exposure Delayed Effects
Prevention
Probiotics
Risk factors
Sucking Behavior - drug effects
Toxicology
Videotape Recording
title Prenatal drug exposure and maternal and infant feeding behaviour
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