Clinical manifestations of protein C deficiency: a spectrum within one family

COMMENT The clinical signs of homozygous protein C deficiency manifest from 2 hours to 2 weeks after birth. 2 Ocular features associated with this condition include vitreous, retinal and subretinal haemorrhage, retinal venous and arterial occlusion, microphthalmos, and leucocoria secondary to retina...

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Bibliographic Details
Published in:British journal of ophthalmology 2001-02, Vol.85 (2), p.238-238
Main Authors: CHURCHILL, AMANDA J, GALLAGHER, MICHAEL J, BRADBURY, JOHN A, MINFORD, ADRIAN MA
Format: Article
Language:English
Subjects:
Cesarean section
Eye Hemorrhage - genetics
Female
Humans
Infant, Newborn
Letters to the Editor
Male
Pedigree
Pharmaceutical industry
Protein C Deficiency - genetics
Proteins
Retinal Diseases - genetics
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Summary:COMMENT The clinical signs of homozygous protein C deficiency manifest from 2 hours to 2 weeks after birth. 2 Ocular features associated with this condition include vitreous, retinal and subretinal haemorrhage, retinal venous and arterial occlusion, microphthalmos, and leucocoria secondary to retinal detachment or persistent hyperplastic primary vitreous. 2 One or both eyes may be affected. Individual V:10 was delivered by emergency caesarean section and a suspected intrauterine cerebral event was confirmed.
ISSN:0007-1161
1468-2079
DOI:10.1136/bjo.85.2.238d