Intraocular pressure rise after small incision cataract surgery: a randomised intraindividual comparison of two dispersive viscoelastic agents

AIM To evaluate the effects of the dispersive viscoelastic agents Ocucoat (hydroxypropyl methylcellulose 2%) and Viscoat (sodium chondroitin sulphate 4%–sodium hyaluronate 3%) on postoperative intraocular pressure (IOP) after bilateral small incision cataract surgery. METHODS This prospective, rando...

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Bibliographic Details
Published in:British journal of ophthalmology 2001-02, Vol.85 (2), p.139-142
Main Authors: Rainer, Georg, Menapace, Rupert, Findl, Oliver, Kiss, Barbara, Petternel, Vanessa, Georgopoulos, Michael, Schneider, Barbara
Format: Article
Language:English
Subjects:
Aged
Aged, 80 and over
Biological and medical sciences
cataract surgery
Cataracts
Chondroitin - adverse effects
Chondroitin Sulfates
Double-Blind Method
Drug Combinations
Endothelium
Eye surgery
Female
Glaucoma
Humans
Hyaluronic Acid - adverse effects
Hypromellose Derivatives
intraocular pressure
Intraoperative Care - adverse effects
Lens diseases
Male
Medical sciences
Methylcellulose - adverse effects
Methylcellulose - analogs & derivatives
Middle Aged
Molecular weight
Ocular Hypertension - chemically induced
Ophthalmology
Original articles - Clinical science
Phacoemulsification - methods
Postoperative Complications
Postoperative Period
Prospective Studies
Sodium
Surgery
Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases
Surgery of the eye and orbit
viscoelastics
Viscosity
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Summary:AIM To evaluate the effects of the dispersive viscoelastic agents Ocucoat (hydroxypropyl methylcellulose 2%) and Viscoat (sodium chondroitin sulphate 4%–sodium hyaluronate 3%) on postoperative intraocular pressure (IOP) after bilateral small incision cataract surgery. METHODS This prospective, randomised study comprised 80 eyes of 40 consecutive patients with age related cataract in both eyes scheduled for bilateral small incision cataract surgery. The patients were randomly assigned to receive Ocucoat or Viscoat during cataract surgery of the first eye. The second eye was operated later and received the other viscoelastic agent. Cataract surgery was performed with a temporal 3.2 mm sutureless posterior limbal incision, phacoemulsification, and implantation of a foldable silicone intraocular lens. The IOP was measured preoperatively as well as 6 hours, 20–24 hours, and 1 week postoperatively. RESULTS At 6 hours after surgery the mean IOP increased by 4.6 (SD 5.1) mm Hg in the Ocucoat group (p
ISSN:0007-1161
1468-2079
DOI:10.1136/bjo.85.2.139