Helicobacter pylori infection in patients with early gastric cancer by the endoscopic phenol red test

Background—An endoscopic procedure that uses a pH indicator called phenol red to assess Helicobacter pyloriinfected gastric mucosa has recently been developed. This test makes it possible to take biopsy specimens from H pylori infected areas. Aim—This test was applied to patients with early gastric...

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Bibliographic Details
Published in:Gut 1998-01, Vol.42 (1), p.20-23
Main Authors: Iseki, K, Tatsuta, M, Iishi, H, Baba, M, Ishiguro, S
Format: Article
Language:English
Subjects:
Adenocarcinoma - microbiology
Adenocarcinoma - pathology
Adenocarcinoma - surgery
Ammonia
Biological and medical sciences
Biopsy
Carcinoma, Signet Ring Cell - microbiology
Carcinoma, Signet Ring Cell - pathology
Carcinoma, Signet Ring Cell - surgery
differentiated adenocarcinoma
Digestive system. Abdomen
endoscopic phenol red test
Endoscopy
Gastrectomy
Gastric cancer
Gastric Mucosa - microbiology
Gastric Mucosa - pathology
Gastroscopy
Helicobacter Infections - diagnosis
Helicobacter pylori
high risk factor
Humans
Indicators and Reagents
Infections
Intestines - pathology
Investigative techniques, diagnostic techniques (general aspects)
Medical sciences
Metaplasia
Mucous membrane
Pharmaceutical industry
Phenols
Phenolsulfonphthalein
Risk Factors
Stomach
Stomach Neoplasms - microbiology
Stomach Neoplasms - pathology
Stomach Neoplasms - surgery
Studies
Tumors
Citations: Items that cite this one
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Description
Summary:Background—An endoscopic procedure that uses a pH indicator called phenol red to assess Helicobacter pyloriinfected gastric mucosa has recently been developed. This test makes it possible to take biopsy specimens from H pylori infected areas. Aim—This test was applied to patients with early gastric cancers to clarify the role of H pylori in gastric carcinogenesis. Subjects—Sixty five patients with early gastric cancer (50 with differentiated adenocarcinoma and 15 with undifferentiated adenocarcinoma). Methods—Patients with early gastric cancer underwent the endoscopic phenol red test before their operation. In this test, areas infected with H pylori can be observed as “coloured” areas where phenol red was turned from yellow to red. Results—H pylori infection was significantly (p
ISSN:0017-5749
1468-3288
1458-3288
DOI:10.1136/gut.42.1.20