Predictive factors for survival of patients with inoperable malignant distal biliary strictures: a practical management guideline

Background—Stenting is the treatment of choice for inoperable malignant strictures of the common bile duct. Criteria for the choice of stents (plastic versus metallic) remain controversial because predicting survival is difficult. Aims—To define prognostic factors in order to improve the cost effect...

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Bibliographic Details
Published in:Gut 1998-01, Vol.42 (1), p.76-80
Main Authors: Prat, F, Chapat, O, Ducot, B, Ponchon, T, Fritsch, J, Choury, A D, Pelletier, G, Buffet, C
Format: Article
Language:English
Subjects:
Adult
Aged
Aged, 80 and over
Bile
Bile Duct Neoplasms - complications
Bile Ducts, Intrahepatic
Biliary and Pancreatic Disease
biliary tract cancer
Biological and medical sciences
Biopsy
Cholangiocarcinoma - complications
Common Bile Duct Diseases - mortality
Common Bile Duct Diseases - pathology
Common Bile Duct Diseases - surgery
Constriction, Pathologic - surgery
Cost-Benefit Analysis
Diseases of the digestive system
endoscopic retrograde cholangiopancreatography
Endoscopy
Female
Histology
Humans
Male
Medical prognosis
Medical sciences
Metastasis
Middle Aged
Morphology
Multivariate Analysis
Palliative Care
palliative treatment
pancreatic cancer
Pancreatic Neoplasms - complications
Prognosis
prognostic factors
Prospective Studies
Radiotherapy. Instrumental treatment. Physiotherapy. Reeducation. Rehabilitation, orthophony, crenotherapy. Diet therapy and various other treatments (general aspects)
Stents
Studies
Surgery
Survival Rate
Tomography
Tumors
Ultrasonic imaging
Weight Loss
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Summary:Background—Stenting is the treatment of choice for inoperable malignant strictures of the common bile duct. Criteria for the choice of stents (plastic versus metallic) remain controversial because predicting survival is difficult. Aims—To define prognostic factors in order to improve the cost effectiveness of endoscopic palliation. Patients—One hundred and one patients were included in a prospective trial. Seven prognostic variables for survival were analysed (age, sex, bilirubinaemia, weight loss, presence of liver metastases, and tumour histology and size). All patients were followed until death or at least one year after inclusion. By the end of the study, 81 (80.2%) patients had died. Results—In univariate analysis, the variables associated with survival were weight loss (p
ISSN:0017-5749
1468-3288
1458-3288
DOI:10.1136/gut.42.1.76