Primary antiphospholipid syndrome with acute myocardial infarction recanalised by PTCA

A 20 year old man with severe chest pain was hospitalised for acute myocardial infarction. Coronary angiography revealed total obstruction of his right coronary artery, which was successfully recanalised by direct percutaneous transluminal coronary angioplasty (PTCA). There was also diffuse thrombi...

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Bibliographic Details
Published in:Heart (British Cardiac Society) 1998-01, Vol.79 (1), p.96-98
Main Authors: Takeuchi, Susumu, Obayashi, Toshihiro, Toyama, Junji
Format: Article
Language:English
Subjects:
acute myocardial infarction
Adult
Angioplasty
Angioplasty, Balloon, Coronary
Anticoagulants
Antiphospholipid Syndrome - complications
Antiphospholipid Syndrome - diagnosis
Antiphospholipid Syndrome - diagnostic imaging
Biological and medical sciences
Cardiology. Vascular system
Case Report
Coronary Angiography
Coronary heart disease
Heart
Heart attacks
Humans
Lupus
Male
Medical sciences
Myocardial Infarction - diagnostic imaging
Myocardial Infarction - etiology
Myocardial Infarction - therapy
percutaneous transluminal coronary angioplasty
primary antiphospholipid syndrome
Veins & arteries
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Summary:A 20 year old man with severe chest pain was hospitalised for acute myocardial infarction. Coronary angiography revealed total obstruction of his right coronary artery, which was successfully recanalised by direct percutaneous transluminal coronary angioplasty (PTCA). There was also diffuse thrombi in the left coronary artery that was not recanalised by perfusion with 3000 U pro-urokinase. Anticoagulant therapy was performed after PTCA. Creatine kinase peaked one day after hospitalisation (4805 U/l). The activated partial thromboplastin time was 62.6 seconds (45%). Plasma anticardiolipin IgG antibodies were high (3.8 and 2.7) in repeated examinations. The PTCA site was patent after three months. Primary antiphospholipid syndrome should be considered as a cause of acute myocardial infarction in young adults, and PTCA with anticoagulant treatment is effective for initial treatment of the syndrome.
ISSN:1355-6037
1468-201X
DOI:10.1136/hrt.79.1.96