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Do patients over 40 years of age benefit from surgical closure of atrial septal defects?
OBJECTIVE To determine the value of surgical closure of atrial septal defects in patients over 40 years of age. METHODS Retrospective analysis of 76 patients (63 women, 13 men), age range 40–62 years (mean (SD) 45.8 (5.1) years), who underwent surgical repair of atrial septal defect. Pre- and postop...
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Published in: | British heart journal 2001-03, Vol.85 (3), p.300-303 |
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creator | Jemielity, M Dyszkiewicz, W Paluszkiewicz, L Perek, B Buczkowski, P Poniz˙yński, A |
description | OBJECTIVE To determine the value of surgical closure of atrial septal defects in patients over 40 years of age. METHODS Retrospective analysis of 76 patients (63 women, 13 men), age range 40–62 years (mean (SD) 45.8 (5.1) years), who underwent surgical repair of atrial septal defect. Pre- and postoperative clinical status (New York Heart Association (NYHA) functional class) was assessed, and ECG,x ray, and echocardiographic investigations performed. Follow up was between 1 and 17 years. RESULTS One operative and one late death occurred during the study period. Before operation, 47 patients (61.8%) were in NYHA functional classes III and IV. After operation, 61 patients (82.4%) were in classes I and II. Four patients had atrial fibrillation before surgery versus nine after surgery. Before operation, 52 patients had intensified pulmonary vascularity compared with only seven after operation. Echocardiographic examination showed a significant reduction in right ventricular dimension (4.10 (0.91)v 2.95 (0.36) cm, p |
doi_str_mv | 10.1136/heart.85.3.300 |
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METHODS Retrospective analysis of 76 patients (63 women, 13 men), age range 40–62 years (mean (SD) 45.8 (5.1) years), who underwent surgical repair of atrial septal defect. Pre- and postoperative clinical status (New York Heart Association (NYHA) functional class) was assessed, and ECG,x ray, and echocardiographic investigations performed. Follow up was between 1 and 17 years. RESULTS One operative and one late death occurred during the study period. Before operation, 47 patients (61.8%) were in NYHA functional classes III and IV. After operation, 61 patients (82.4%) were in classes I and II. Four patients had atrial fibrillation before surgery versus nine after surgery. Before operation, 52 patients had intensified pulmonary vascularity compared with only seven after operation. Echocardiographic examination showed a significant reduction in right ventricular dimension (4.10 (0.91)v 2.95 (0.36) cm, p < 0.001). No residual intracardiac shunts were identified on echocardiographic follow up. CONCLUSIONS Surgical closure of atrial septal defects in patients over 40 years old can improve their clinical status and prevent right ventricular dilatation and insufficiency.</description><identifier>ISSN: 1355-6037</identifier><identifier>ISSN: 0007-0769</identifier><identifier>EISSN: 1468-201X</identifier><identifier>DOI: 10.1136/heart.85.3.300</identifier><identifier>PMID: 11179271</identifier><language>eng</language><publisher>London: BMJ Publishing Group Ltd and British Cardiovascular Society</publisher><subject>Adult ; Age Factors ; Anticoagulants ; Arrhythmias, Cardiac - etiology ; atrial septal defect ; Atrial septal defects ; Biological and medical sciences ; cardiac surgery ; Cardiology. Vascular system ; Congenital heart diseases. Malformations of the aorta, pulmonary vessels and vena cava ; Defects ; Dyspnea ; Female ; Heart ; Heart Septal Defects, Atrial - complications ; Heart Septal Defects, Atrial - mortality ; Heart Septal Defects, Atrial - physiopathology ; Heart Septal Defects, Atrial - surgery ; Heart Ventricles - anatomy & histology ; Heart Ventricles - diagnostic imaging ; Humans ; Interventional Cardiology Surgery ; Ischemia ; Male ; Medical sciences ; Middle Aged ; Middle aged persons ; Patient Satisfaction ; Patients ; Retrospective Studies ; Surgery ; Thromboembolism ; Ultrasonography</subject><ispartof>British heart journal, 2001-03, Vol.85 (3), p.300-303</ispartof><rights>British Cardiac Society</rights><rights>2001 INIST-CNRS</rights><rights>COPYRIGHT 2001 BMJ Publishing Group Ltd.</rights><rights>Copyright: 2001 British Cardiac Society</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-b589t-fad04f42fd22c6fae469cb512512587c97f84b752c0fd52f9347fb18e9a39ffa3</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC1729662/pdf/$$EPDF$$P50$$Gpubmedcentral$$H</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC1729662/$$EHTML$$P50$$Gpubmedcentral$$H</linktohtml><link.rule.ids>230,314,727,780,784,885,27923,27924,53790,53792</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=889431$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/11179271$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Jemielity, M</creatorcontrib><creatorcontrib>Dyszkiewicz, W</creatorcontrib><creatorcontrib>Paluszkiewicz, L</creatorcontrib><creatorcontrib>Perek, B</creatorcontrib><creatorcontrib>Buczkowski, P</creatorcontrib><creatorcontrib>Poniz˙yński, A</creatorcontrib><title>Do patients over 40 years of age benefit from surgical closure of atrial septal defects?</title><title>British heart journal</title><addtitle>Heart</addtitle><description>OBJECTIVE To determine the value of surgical closure of atrial septal defects in patients over 40 years of age. METHODS Retrospective analysis of 76 patients (63 women, 13 men), age range 40–62 years (mean (SD) 45.8 (5.1) years), who underwent surgical repair of atrial septal defect. Pre- and postoperative clinical status (New York Heart Association (NYHA) functional class) was assessed, and ECG,x ray, and echocardiographic investigations performed. Follow up was between 1 and 17 years. RESULTS One operative and one late death occurred during the study period. Before operation, 47 patients (61.8%) were in NYHA functional classes III and IV. After operation, 61 patients (82.4%) were in classes I and II. Four patients had atrial fibrillation before surgery versus nine after surgery. Before operation, 52 patients had intensified pulmonary vascularity compared with only seven after operation. Echocardiographic examination showed a significant reduction in right ventricular dimension (4.10 (0.91)v 2.95 (0.36) cm, p < 0.001). No residual intracardiac shunts were identified on echocardiographic follow up. CONCLUSIONS Surgical closure of atrial septal defects in patients over 40 years old can improve their clinical status and prevent right ventricular dilatation and insufficiency.</description><subject>Adult</subject><subject>Age Factors</subject><subject>Anticoagulants</subject><subject>Arrhythmias, Cardiac - etiology</subject><subject>atrial septal defect</subject><subject>Atrial septal defects</subject><subject>Biological and medical sciences</subject><subject>cardiac surgery</subject><subject>Cardiology. Vascular system</subject><subject>Congenital heart diseases. Malformations of the aorta, pulmonary vessels and vena cava</subject><subject>Defects</subject><subject>Dyspnea</subject><subject>Female</subject><subject>Heart</subject><subject>Heart Septal Defects, Atrial - complications</subject><subject>Heart Septal Defects, Atrial - mortality</subject><subject>Heart Septal Defects, Atrial - physiopathology</subject><subject>Heart Septal Defects, Atrial - surgery</subject><subject>Heart Ventricles - anatomy & histology</subject><subject>Heart Ventricles - diagnostic imaging</subject><subject>Humans</subject><subject>Interventional Cardiology Surgery</subject><subject>Ischemia</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Middle Aged</subject><subject>Middle aged persons</subject><subject>Patient Satisfaction</subject><subject>Patients</subject><subject>Retrospective Studies</subject><subject>Surgery</subject><subject>Thromboembolism</subject><subject>Ultrasonography</subject><issn>1355-6037</issn><issn>0007-0769</issn><issn>1468-201X</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2001</creationdate><recordtype>article</recordtype><recordid>eNqFkl1rFDEUhgdRbK3eeikDgiA4az4mk-RGKaurYlEQLb0LmczJNnVmsiazxf57z3aXbZWCJJCT5Ml7PnKK4iklM0p58_ocbJpmSsz4jBNyrzikdaMqRujZfbS5EFVDuDwoHuV8QQiptWoeFgeUUqmZpIfF2btYruwUYJxyGS8hlTUpr1AUd760SyhbGMGHqfQpDmVep2Vwti9dH9GGa2hKAU8yrCZcOvDgpvz2cfHA2z7Dk916VPxYvP8-_1idfP3waX58UrVC6anytiO1r5nvGHONt1A32rWCss1U0mnpVd1KwRzxnWBe81r6lirQlmvvLT8q3mx1V-t2gM5hIsn2ZpXCYNOViTaYv2_GcG6W8dJQyXTTMBR4sRNI8dca8mSGkB30vR0hrrORpBFEUo7g83_Ai7hOIyaHWopITaTUSL3aUkvbgwmjj-jVLbGI6DxuSonHx0gKzaVEvLoDx9HBENxd_GzLuxRzTuD3mVJiNh1hrjvCKGG4wY7AB89u1-cG37XArbRsxp_1yY4u5D2nlK45vYkz5Al-729t-mkayaUwX07n5tspWwj6mZkF8i-3fDtc_C_EP_4w24Q</recordid><startdate>20010301</startdate><enddate>20010301</enddate><creator>Jemielity, M</creator><creator>Dyszkiewicz, W</creator><creator>Paluszkiewicz, L</creator><creator>Perek, B</creator><creator>Buczkowski, P</creator><creator>Poniz˙yński, A</creator><general>BMJ Publishing Group Ltd and British Cardiovascular Society</general><general>BMJ</general><general>BMJ Publishing Group Ltd</general><general>BMJ Publishing Group LTD</general><scope>BSCLL</scope><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>88I</scope><scope>8AF</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>BTHHO</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>HCIFZ</scope><scope>K9.</scope><scope>M0S</scope><scope>M1P</scope><scope>M2P</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>Q9U</scope><scope>7X8</scope><scope>5PM</scope></search><sort><creationdate>20010301</creationdate><title>Do patients over 40 years of age benefit from surgical closure of atrial septal defects?</title><author>Jemielity, M ; Dyszkiewicz, W ; Paluszkiewicz, L ; Perek, B ; Buczkowski, P ; Poniz˙yński, A</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-b589t-fad04f42fd22c6fae469cb512512587c97f84b752c0fd52f9347fb18e9a39ffa3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2001</creationdate><topic>Adult</topic><topic>Age Factors</topic><topic>Anticoagulants</topic><topic>Arrhythmias, Cardiac - etiology</topic><topic>atrial septal defect</topic><topic>Atrial septal defects</topic><topic>Biological and medical sciences</topic><topic>cardiac surgery</topic><topic>Cardiology. Vascular system</topic><topic>Congenital heart diseases. Malformations of the aorta, pulmonary vessels and vena cava</topic><topic>Defects</topic><topic>Dyspnea</topic><topic>Female</topic><topic>Heart</topic><topic>Heart Septal Defects, Atrial - complications</topic><topic>Heart Septal Defects, Atrial - mortality</topic><topic>Heart Septal Defects, Atrial - physiopathology</topic><topic>Heart Septal Defects, Atrial - surgery</topic><topic>Heart Ventricles - anatomy & histology</topic><topic>Heart Ventricles - diagnostic imaging</topic><topic>Humans</topic><topic>Interventional Cardiology Surgery</topic><topic>Ischemia</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Middle Aged</topic><topic>Middle aged persons</topic><topic>Patient Satisfaction</topic><topic>Patients</topic><topic>Retrospective Studies</topic><topic>Surgery</topic><topic>Thromboembolism</topic><topic>Ultrasonography</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Jemielity, M</creatorcontrib><creatorcontrib>Dyszkiewicz, W</creatorcontrib><creatorcontrib>Paluszkiewicz, L</creatorcontrib><creatorcontrib>Perek, B</creatorcontrib><creatorcontrib>Buczkowski, P</creatorcontrib><creatorcontrib>Poniz˙yński, A</creatorcontrib><collection>Istex</collection><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>Science Database (Alumni Edition)</collection><collection>STEM Database</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni)</collection><collection>ProQuest Central</collection><collection>ProQuest Central Essentials</collection><collection>AUTh Library subscriptions: ProQuest Central</collection><collection>BMJ Journals</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>SciTech Premium Collection</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Science Database</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>ProQuest Central Basic</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>British heart journal</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Jemielity, M</au><au>Dyszkiewicz, W</au><au>Paluszkiewicz, L</au><au>Perek, B</au><au>Buczkowski, P</au><au>Poniz˙yński, A</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Do patients over 40 years of age benefit from surgical closure of atrial septal defects?</atitle><jtitle>British heart journal</jtitle><addtitle>Heart</addtitle><date>2001-03-01</date><risdate>2001</risdate><volume>85</volume><issue>3</issue><spage>300</spage><epage>303</epage><pages>300-303</pages><issn>1355-6037</issn><issn>0007-0769</issn><eissn>1468-201X</eissn><abstract>OBJECTIVE To determine the value of surgical closure of atrial septal defects in patients over 40 years of age. METHODS Retrospective analysis of 76 patients (63 women, 13 men), age range 40–62 years (mean (SD) 45.8 (5.1) years), who underwent surgical repair of atrial septal defect. Pre- and postoperative clinical status (New York Heart Association (NYHA) functional class) was assessed, and ECG,x ray, and echocardiographic investigations performed. Follow up was between 1 and 17 years. RESULTS One operative and one late death occurred during the study period. Before operation, 47 patients (61.8%) were in NYHA functional classes III and IV. After operation, 61 patients (82.4%) were in classes I and II. Four patients had atrial fibrillation before surgery versus nine after surgery. Before operation, 52 patients had intensified pulmonary vascularity compared with only seven after operation. Echocardiographic examination showed a significant reduction in right ventricular dimension (4.10 (0.91)v 2.95 (0.36) cm, p < 0.001). No residual intracardiac shunts were identified on echocardiographic follow up. CONCLUSIONS Surgical closure of atrial septal defects in patients over 40 years old can improve their clinical status and prevent right ventricular dilatation and insufficiency.</abstract><cop>London</cop><pub>BMJ Publishing Group Ltd and British Cardiovascular Society</pub><pmid>11179271</pmid><doi>10.1136/heart.85.3.300</doi><tpages>4</tpages><oa>free_for_read</oa></addata></record> |
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subjects | Adult Age Factors Anticoagulants Arrhythmias, Cardiac - etiology atrial septal defect Atrial septal defects Biological and medical sciences cardiac surgery Cardiology. Vascular system Congenital heart diseases. Malformations of the aorta, pulmonary vessels and vena cava Defects Dyspnea Female Heart Heart Septal Defects, Atrial - complications Heart Septal Defects, Atrial - mortality Heart Septal Defects, Atrial - physiopathology Heart Septal Defects, Atrial - surgery Heart Ventricles - anatomy & histology Heart Ventricles - diagnostic imaging Humans Interventional Cardiology Surgery Ischemia Male Medical sciences Middle Aged Middle aged persons Patient Satisfaction Patients Retrospective Studies Surgery Thromboembolism Ultrasonography |
title | Do patients over 40 years of age benefit from surgical closure of atrial septal defects? |
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