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Do patients over 40 years of age benefit from surgical closure of atrial septal defects?

OBJECTIVE To determine the value of surgical closure of atrial septal defects in patients over 40 years of age. METHODS Retrospective analysis of 76 patients (63 women, 13 men), age range 40–62 years (mean (SD) 45.8 (5.1) years), who underwent surgical repair of atrial septal defect. Pre- and postop...

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Published in:British heart journal 2001-03, Vol.85 (3), p.300-303
Main Authors: Jemielity, M, Dyszkiewicz, W, Paluszkiewicz, L, Perek, B, Buczkowski, P, Poniz˙yński, A
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container_title British heart journal
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creator Jemielity, M
Dyszkiewicz, W
Paluszkiewicz, L
Perek, B
Buczkowski, P
Poniz˙yński, A
description OBJECTIVE To determine the value of surgical closure of atrial septal defects in patients over 40 years of age. METHODS Retrospective analysis of 76 patients (63 women, 13 men), age range 40–62 years (mean (SD) 45.8 (5.1) years), who underwent surgical repair of atrial septal defect. Pre- and postoperative clinical status (New York Heart Association (NYHA) functional class) was assessed, and ECG,x ray, and echocardiographic investigations performed. Follow up was between 1 and 17 years. RESULTS One operative and one late death occurred during the study period. Before operation, 47 patients (61.8%) were in NYHA functional classes III and IV. After operation, 61 patients (82.4%) were in classes I and II. Four patients had atrial fibrillation before surgery versus nine after surgery. Before operation, 52 patients had intensified pulmonary vascularity compared with only seven after operation. Echocardiographic examination showed a significant reduction in right ventricular dimension (4.10 (0.91)v 2.95 (0.36) cm, p 
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METHODS Retrospective analysis of 76 patients (63 women, 13 men), age range 40–62 years (mean (SD) 45.8 (5.1) years), who underwent surgical repair of atrial septal defect. Pre- and postoperative clinical status (New York Heart Association (NYHA) functional class) was assessed, and ECG,x ray, and echocardiographic investigations performed. Follow up was between 1 and 17 years. RESULTS One operative and one late death occurred during the study period. Before operation, 47 patients (61.8%) were in NYHA functional classes III and IV. After operation, 61 patients (82.4%) were in classes I and II. Four patients had atrial fibrillation before surgery versus nine after surgery. Before operation, 52 patients had intensified pulmonary vascularity compared with only seven after operation. Echocardiographic examination showed a significant reduction in right ventricular dimension (4.10 (0.91)v 2.95 (0.36) cm, p &lt; 0.001). No residual intracardiac shunts were identified on echocardiographic follow up. CONCLUSIONS Surgical closure of atrial septal defects in patients over 40 years old can improve their clinical status and prevent right ventricular dilatation and insufficiency.</description><identifier>ISSN: 1355-6037</identifier><identifier>ISSN: 0007-0769</identifier><identifier>EISSN: 1468-201X</identifier><identifier>DOI: 10.1136/heart.85.3.300</identifier><identifier>PMID: 11179271</identifier><language>eng</language><publisher>London: BMJ Publishing Group Ltd and British Cardiovascular Society</publisher><subject>Adult ; Age Factors ; Anticoagulants ; Arrhythmias, Cardiac - etiology ; atrial septal defect ; Atrial septal defects ; Biological and medical sciences ; cardiac surgery ; Cardiology. Vascular system ; Congenital heart diseases. Malformations of the aorta, pulmonary vessels and vena cava ; Defects ; Dyspnea ; Female ; Heart ; Heart Septal Defects, Atrial - complications ; Heart Septal Defects, Atrial - mortality ; Heart Septal Defects, Atrial - physiopathology ; Heart Septal Defects, Atrial - surgery ; Heart Ventricles - anatomy &amp; histology ; Heart Ventricles - diagnostic imaging ; Humans ; Interventional Cardiology Surgery ; Ischemia ; Male ; Medical sciences ; Middle Aged ; Middle aged persons ; Patient Satisfaction ; Patients ; Retrospective Studies ; Surgery ; Thromboembolism ; Ultrasonography</subject><ispartof>British heart journal, 2001-03, Vol.85 (3), p.300-303</ispartof><rights>British Cardiac Society</rights><rights>2001 INIST-CNRS</rights><rights>COPYRIGHT 2001 BMJ Publishing Group Ltd.</rights><rights>Copyright: 2001 British Cardiac Society</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-b589t-fad04f42fd22c6fae469cb512512587c97f84b752c0fd52f9347fb18e9a39ffa3</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC1729662/pdf/$$EPDF$$P50$$Gpubmedcentral$$H</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC1729662/$$EHTML$$P50$$Gpubmedcentral$$H</linktohtml><link.rule.ids>230,314,727,780,784,885,27923,27924,53790,53792</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&amp;idt=889431$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/11179271$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Jemielity, M</creatorcontrib><creatorcontrib>Dyszkiewicz, W</creatorcontrib><creatorcontrib>Paluszkiewicz, L</creatorcontrib><creatorcontrib>Perek, B</creatorcontrib><creatorcontrib>Buczkowski, P</creatorcontrib><creatorcontrib>Poniz˙yński, A</creatorcontrib><title>Do patients over 40 years of age benefit from surgical closure of atrial septal defects?</title><title>British heart journal</title><addtitle>Heart</addtitle><description>OBJECTIVE To determine the value of surgical closure of atrial septal defects in patients over 40 years of age. METHODS Retrospective analysis of 76 patients (63 women, 13 men), age range 40–62 years (mean (SD) 45.8 (5.1) years), who underwent surgical repair of atrial septal defect. Pre- and postoperative clinical status (New York Heart Association (NYHA) functional class) was assessed, and ECG,x ray, and echocardiographic investigations performed. Follow up was between 1 and 17 years. RESULTS One operative and one late death occurred during the study period. Before operation, 47 patients (61.8%) were in NYHA functional classes III and IV. After operation, 61 patients (82.4%) were in classes I and II. Four patients had atrial fibrillation before surgery versus nine after surgery. Before operation, 52 patients had intensified pulmonary vascularity compared with only seven after operation. Echocardiographic examination showed a significant reduction in right ventricular dimension (4.10 (0.91)v 2.95 (0.36) cm, p &lt; 0.001). No residual intracardiac shunts were identified on echocardiographic follow up. CONCLUSIONS Surgical closure of atrial septal defects in patients over 40 years old can improve their clinical status and prevent right ventricular dilatation and insufficiency.</description><subject>Adult</subject><subject>Age Factors</subject><subject>Anticoagulants</subject><subject>Arrhythmias, Cardiac - etiology</subject><subject>atrial septal defect</subject><subject>Atrial septal defects</subject><subject>Biological and medical sciences</subject><subject>cardiac surgery</subject><subject>Cardiology. Vascular system</subject><subject>Congenital heart diseases. 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METHODS Retrospective analysis of 76 patients (63 women, 13 men), age range 40–62 years (mean (SD) 45.8 (5.1) years), who underwent surgical repair of atrial septal defect. Pre- and postoperative clinical status (New York Heart Association (NYHA) functional class) was assessed, and ECG,x ray, and echocardiographic investigations performed. Follow up was between 1 and 17 years. RESULTS One operative and one late death occurred during the study period. Before operation, 47 patients (61.8%) were in NYHA functional classes III and IV. After operation, 61 patients (82.4%) were in classes I and II. Four patients had atrial fibrillation before surgery versus nine after surgery. Before operation, 52 patients had intensified pulmonary vascularity compared with only seven after operation. Echocardiographic examination showed a significant reduction in right ventricular dimension (4.10 (0.91)v 2.95 (0.36) cm, p &lt; 0.001). No residual intracardiac shunts were identified on echocardiographic follow up. CONCLUSIONS Surgical closure of atrial septal defects in patients over 40 years old can improve their clinical status and prevent right ventricular dilatation and insufficiency.</abstract><cop>London</cop><pub>BMJ Publishing Group Ltd and British Cardiovascular Society</pub><pmid>11179271</pmid><doi>10.1136/heart.85.3.300</doi><tpages>4</tpages><oa>free_for_read</oa></addata></record>
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identifier ISSN: 1355-6037
ispartof British heart journal, 2001-03, Vol.85 (3), p.300-303
issn 1355-6037
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1468-201X
language eng
recordid cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_1729662
source PubMed Central
subjects Adult
Age Factors
Anticoagulants
Arrhythmias, Cardiac - etiology
atrial septal defect
Atrial septal defects
Biological and medical sciences
cardiac surgery
Cardiology. Vascular system
Congenital heart diseases. Malformations of the aorta, pulmonary vessels and vena cava
Defects
Dyspnea
Female
Heart
Heart Septal Defects, Atrial - complications
Heart Septal Defects, Atrial - mortality
Heart Septal Defects, Atrial - physiopathology
Heart Septal Defects, Atrial - surgery
Heart Ventricles - anatomy & histology
Heart Ventricles - diagnostic imaging
Humans
Interventional Cardiology Surgery
Ischemia
Male
Medical sciences
Middle Aged
Middle aged persons
Patient Satisfaction
Patients
Retrospective Studies
Surgery
Thromboembolism
Ultrasonography
title Do patients over 40 years of age benefit from surgical closure of atrial septal defects?
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