The diagnosis of hypertrophic cardiomyopathy

Because of the time consuming nature of these molecular genetic studies, they are only currently available in research centres. Atrial fibrillation Atrial fibrillation An important cause of morbidity: congestive heart failure, risk of systemic emboli, rarely syncope Almost always related to left atr...

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Bibliographic Details
Published in:Heart (British Cardiac Society) 2001-12, Vol.86 (6), p.709-714
Main Author: Wigle, E Douglas
Format: Article
Language:English
Subjects:
Cardiac arrhythmia
Cardiomyopathy
Education in Heart
Electrocardiography
Family medical history
Heart failure
Mortality
Mutation
NMR
Nuclear magnetic resonance
Proteins
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Summary:Because of the time consuming nature of these molecular genetic studies, they are only currently available in research centres. Atrial fibrillation Atrial fibrillation An important cause of morbidity: congestive heart failure, risk of systemic emboli, rarely syncope Almost always related to left atrial enlargement, which is most frequently seen in subaortic obstructive HCM (caused by concomitant mitral regurgitation) or in the presence of systolic and/or diastolic dysfunction In the presence of subaortic obstructive HCM, atrial fibrillation may lead to a mistaken diagnosis of mitral regurgitation because of the apical murmur Every attempt should be made to restore sinus rhythm pharmacologically or by cardioversion Conclusion HCM is a heterogeneous disease, both genotypically and phenotypically, and is often a diagnostic challenge.
ISSN:1355-6037
1468-201X
DOI:10.1136/heart.86.6.709