Guidelines for a genetic risk based approach to advising women with a family history of breast cancer

A family history of breast cancer has long been recognised as a significant risk factor for breast cancer. Quantifying that risk has been approached in publications and practically in a number of different ways. Increasingly regional genetics departments are called upon to help clarify guidelines fo...

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Bibliographic Details
Published in:Journal of medical genetics 2000-03, Vol.37 (3), p.203-209
Main Authors: Eccles, D M, Evans, D G R, Mackay, J
Format: Article
Language:English
Subjects:
Age
Biological and medical sciences
Breast cancer
Clinical Genetics in Practice
Clinics
Family medical history
Funding
genetic risk
Genetics
guidelines
Gynecology. Andrology. Obstetrics
Health risk assessment
Mammary gland diseases
Mammography
Medical research
Medical sciences
Oncology
Tumors
Womens health
Womens history
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Summary:A family history of breast cancer has long been recognised as a significant risk factor for breast cancer. Quantifying that risk has been approached in publications and practically in a number of different ways. Increasingly regional genetics departments are called upon to help clarify guidelines for referral of women with a family history of breast cancer for genetic testing and to clarify breast cancer risk for women seeking early mammographic screening. This paper represents the current consensus guidelines from the UK Cancer Family Study Group and discusses some of the difficulties surrounding genetic risk estimation.
ISSN:0022-2593
1468-6244
1468-6244
DOI:10.1136/jmg.37.3.203