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Vasculitic neuropathies
The link between infection and systemic vasculitis comes from the prevalence of hepatitis B surface antigens and antihepatitis B virus antibodies in polyarteritis nodosa and hepatitis C infections and mixed cryoglobulinaemia related vasculitis. 32 34 35 Neuropathies also occur in Lyme disease and HI...
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Published in: | Journal of neurology, neurosurgery and psychiatry neurosurgery and psychiatry, 2000-03, Vol.68 (3), p.271-274 |
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Main Author: | |
Format: | Article |
Language: | English |
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Citations: | Items that cite this one |
Online Access: | Get full text |
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Summary: | The link between infection and systemic vasculitis comes from the prevalence of hepatitis B surface antigens and antihepatitis B virus antibodies in polyarteritis nodosa and hepatitis C infections and mixed cryoglobulinaemia related vasculitis. 32 34 35 Neuropathies also occur in Lyme disease and HIV infections; among the reported mechanisms is a vasculitis. 36 37 The appearance of a CD8 T cell mediated vasculitis in patients with HIV with low peripheral blood CD4 T cell counts is striking. Endothelial cells as well as T lymphocytes and macrophages release soluble forms of adhesion molecules on cytokine stimulation; they are considered a consequence of endothelial cell activation in response to inflammatory stimuli. |
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ISSN: | 0022-3050 1468-330X |
DOI: | 10.1136/jnnp.68.3.271 |