Metabolic and electrophysiological validation of functional MRI

OBJECTIVES Although functional MRI is widely used for preoperative planning and intraoperative neuronavigation, its accuracy to depict the site of neuronal activity is not exactly known. Experience with methods that may validate fMRI data and the results obtained when coregistering fMRI with differe...

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Bibliographic Details
Published in:Journal of neurology, neurosurgery and psychiatry neurosurgery and psychiatry, 2001-12, Vol.71 (6), p.762-771
Main Authors: Krings, T, Schreckenberger, M, Rohde, V, Foltys, H, Spetzger, U, Sabri, O, Reinges, M H T, Kemeny, S, Meyer, P T, Möller-Hartmann, W, Korinth, M, Gilsbach, J M, Buell, U, Thron, A
Format: Article
Language:English
Subjects:
Accuracy
Adult
Aged
Bias
Biological and medical sciences
Brain
Brain cancer
Brain Mapping - instrumentation
Brain Mapping - methods
Brain Neoplasms - diagnosis
Brain Neoplasms - metabolism
Brain Neoplasms - physiopathology
Brain Neoplasms - surgery
Electrodiagnosis - instrumentation
Electrodiagnosis - methods
Electrodiagnosis - standards
Electrophysiology - instrumentation
Electrophysiology - methods
Electrophysiology - standards
Evaluation
Female
Fluorodeoxyglucose F18
functional MRI
Humans
Investigative techniques, diagnostic techniques (general aspects)
Localization
Magnetic resonance imaging
Magnetic Resonance Imaging - instrumentation
Magnetic Resonance Imaging - methods
Magnetic Resonance Imaging - standards
Magnetics - instrumentation
Male
Medical sciences
Middle Aged
motor cortex
Nervous system
Patients
PET imaging
Preoperative Care
presurgical planning
Psychomotor Performance
Radiodiagnosis. Nmr imagery. Nmr spectrometry
Radiopharmaceuticals
Sensitivity and Specificity
Signal Processing, Computer-Assisted
Stereotaxic Techniques - instrumentation
Stereotaxic Techniques - standards
Tomography, Emission-Computed - instrumentation
Tomography, Emission-Computed - methods
Tomography, Emission-Computed - standards
Transcranial magnetic stimulation
Work stations
Citations: Items that cite this one
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Description
Summary:OBJECTIVES Although functional MRI is widely used for preoperative planning and intraoperative neuronavigation, its accuracy to depict the site of neuronal activity is not exactly known. Experience with methods that may validate fMRI data and the results obtained when coregistering fMRI with different preoperative and intraoperative mapping modalities including metabolically based 18F-fluorodeoxyglucose PET, electrophysiologcally based transcranial magnetic stimulation (TMS), and direct electrical cortical stimulation (DECS) are described. METHODS Fifty patients were included. PET was performed in 30, TMS in 10, and DECS in 41 patients. After coregistration using a frameless stereotactic system, results were grouped into overlapping (
ISSN:0022-3050
1468-330X
DOI:10.1136/jnnp.71.6.762