The probability of middle cerebral artery MRA flow signal abnormality with quantified CT ischaemic change: targets for future therapeutic studies

Objectives: In this study we define the probability of vascular abnormality in the middle cerebral artery (MCA) territory according to the extent of ischaemic change seen using computed tomography (CT). We assessed the sensitivity and specificity of the hyperdense middle cerebral artery (HMCA) and t...

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Bibliographic Details
Published in:Journal of neurology, neurosurgery and psychiatry neurosurgery and psychiatry, 2004-10, Vol.75 (10), p.1426-1430
Main Authors: Barber, P A, Demchuk, A M, Hill, M D, Pexman, J H Warwick, Hudon, M E, Frayne, R, Buchan, A M
Format: Article
Language:English
Subjects:
ACAs
acute stroke
Aged
Aged, 80 and over
Alberta Stroke Program Early CT Score
anterior cerebral artery
ASPECTS
basilar artery
Biological and medical sciences
Brain Ischemia - diagnostic imaging
Brain Ischemia - etiology
Brain Ischemia - pathology
computed tomography
Diffusion Magnetic Resonance Imaging
diffusion weighted imaging
Doppler effect
DWI
Female
FLAIR
fluid attenuated inversion recovery
HMCA
Humans
hyperdense MCA
ICA
Image Processing, Computer-Assisted
Infarction, Middle Cerebral Artery - diagnostic imaging
Infarction, Middle Cerebral Artery - pathology
internal carotid artery
Investigative techniques, diagnostic techniques (general aspects)
Magnetic Resonance Angiography
Male
MCA
Medical imaging
Medical sciences
Middle Aged
middle cerebral artery
modified Rankin scale
MRA
mRS
National Institute of Health Stroke Scale
Nervous system
Neurology
NIHSS
PCA
posterior cerebral artery
Predictive Value of Tests
PROACT-II
ProLyse for Acute Cerebral Thromboembolism trial
Sensitivity and Specificity
Stroke
tissue plasminogen activator
Tomography, X-Ray Computed
tPA
Ultrasonic investigative techniques
Vascular diseases and vascular malformations of the nervous system
vascular occlusion
Veins & arteries
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Description
Summary:Objectives: In this study we define the probability of vascular abnormality in the middle cerebral artery (MCA) territory according to the extent of ischaemic change seen using computed tomography (CT). We assessed the sensitivity and specificity of the hyperdense middle cerebral artery (HMCA) and the “dot” sign using magnetic resonance angiography (MRA). Methods: Patients presenting with ischaemic stroke had a CT scan (
ISSN:0022-3050
1468-330X
DOI:10.1136/jnnp.2003.029389