Validity of language lateralisation by unilateral intracarotid Wada test

(1) Little is known about the relative susceptibility to the effect of amobarbital of language areas compared with damaged motor cortex. [...]it may be that a low dose of amytal (which 100 mg is) does impair a partially damaged motor cortex when language areas still maintain sufficient function to s...

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Bibliographic Details
Published in:Journal of neurology, neurosurgery and psychiatry neurosurgery and psychiatry, 2004-09, Vol.75 (9), p.1367-1367; author reply 1368
Main Authors: Schulze-Bonhage, A, Quiske, A
Format: Article
Language:English
Subjects:
Aphasia
Correspondence
Epilepsy
Epilepsy - surgery
Functional Laterality
Hemiplegia - etiology
Humans
Language
language lateralisation
Magnetic Resonance Imaging
Medical History Taking
Medical imaging
Motor Cortex - pathology
Neuronal Plasticity
Neuropsychological Tests
Patients
Reproducibility of Results
Surgery
Validity
Wada test
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Summary:(1) Little is known about the relative susceptibility to the effect of amobarbital of language areas compared with damaged motor cortex. [...]it may be that a low dose of amytal (which 100 mg is) does impair a partially damaged motor cortex when language areas still maintain sufficient function to solve the tasks tested during the Wada procedure. No clinical data are available on the effect of amobarbital on the damaged motor cortex. [...]the effectiveness of an initial high dose of amobarbital, as well as incomplete inactivation of different MCA areas, remains an interesting speculation.
ISSN:0022-3050
1468-330X