Congenital dumbbell neuroblastoma mimicking birth trauma

Early diagnosis can improve outcome, 2, 3 and neuroblastoma diagnosed even in the prenatal period has been reported to have excellent prognosis. 4 Although congenital dumbbell neuroblastomas are rare, spinal cord compression and involvement of the peripheral nerves or nerve plexus are not uncommon w...

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Bibliographic Details
Published in:Journal of neurology, neurosurgery and psychiatry neurosurgery and psychiatry, 2005-01, Vol.76 (1), p.143-144
Main Authors: Nejat, F, Zabihyan Sigarchi, S, IzadYar, M
Format: Article
Language:English
Subjects:
Abdomen
Biopsy
Chemotherapy
Childbirth & labor
congenital neuroblastoma
Diagnosis, Differential
Humans
Infant
Infant, Newborn
Letter
Male
neonate
Neuroblastoma
Neuroblastoma - congenital
Neuroblastoma - diagnosis
NMR
Nuclear magnetic resonance
Obstetrics
Paralysis, Obstetric - diagnosis
Retroperitoneal Neoplasms - congenital
Retroperitoneal Neoplasms - diagnosis
Spinal cord
unilateral leg palsy
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Summary:Early diagnosis can improve outcome, 2, 3 and neuroblastoma diagnosed even in the prenatal period has been reported to have excellent prognosis. 4 Although congenital dumbbell neuroblastomas are rare, spinal cord compression and involvement of the peripheral nerves or nerve plexus are not uncommon with abdominal neuroblastoma. 5 The incidence of intraspinal involvement of neuroblastoma varies between 6% and 24%. 6, 7 Intraspinal neuroblastoma is a direct extension of a peripheral tumour. 8 Dumbbell neuroblastoma is the commonest malignant cause of spinal cord or nerve root compression in young children and is regarded as an unresectable tumour. 7 Chemotherapy should be considered for patients with partial deficits and surgical decompression should be reserved for children with recent onset of severe neurological dysfunction or deterioration in a 24-72 hour period. 7 We treated case 1 with chemotherapy only, because his neurological deficit had been observed four months ago and was not progressive.
ISSN:0022-3050
1468-330X
DOI:10.1136/jnnp.2003.027912