Oral immunization of interleukin-4 (IL-4) knockout mice with a recombinant Salmonella strain or cholera toxin reveals that CD4+ Th2 cells producing IL-6 and IL-10 are associated with mucosal immunoglobulin A responses

• Published in: Infection and Immunity 1996-05, Vol.64 (5), p.1516-1525
• Main Authors: OKAHASHI, N, YAMAMOTO, M, VANCOTT, J. L, CHATFIELD, S. N, ROBERTS, M, BLUETHMANN, H, HIROI, T, KIYONO, H, MCGHEE, J. R, KAUFMANN, S. H. E
• Format: Article
• Language: English
• Subjects: Adjuvants, Immunologic - administration & dosage; Administration, Oral; Analysis of the immune response. Humoral and cellular immunity; Animals; Antibody production; Antigens, Bacterial - administration & dosage; Biological and medical sciences; Cholera Toxin - administration & dosage; Cholera Toxin - immunology; Cytokines - biosynthesis; Cytokines - genetics; Fundamental and applied biological sciences. Psychology; Fundamental immunology; Immunization; Immunobiology; Immunoglobulin A - biosynthesis; Immunoglobulin E - blood; Immunoglobulin G - blood; Immunoglobulin G - classification; Interleukin-10 - biosynthesis; Interleukin-10 - genetics; Interleukin-4 - genetics; Interleukin-4 - physiology; Interleukin-6 - biosynthesis; Interleukin-6 - genetics; Mice; Mice, Inbred C57BL; Mice, Knockout; Mucous Membrane - immunology; Rats; Rats, Inbred F344; RNA, Messenger - genetics; RNA, Messenger - metabolism; Salmonella - immunology; Tetanus Toxin - administration & dosage; Tetanus Toxin - immunology; Th2 Cells - immunology
• ISSN: 0019-9567; 1098-5522
• DOI: 10.1128/IAI.64.5.1516-1525.1996

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