Myocardial infarction, seizure and an abnormal head CT scan

[...]it is unclear if this seizure was related to the history of seizures. Relative hypoxia due to increased ictal metabolism, with an increase in local pCO2 and lactate, results in local vasodilatation and loss of autoregulation. 5 Systemically there is an increase in blood pressure and decrease in...

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Bibliographic Details
Published in:Postgraduate medical journal 1999-12, Vol.75 (890), p.757-759
Main Authors: Selvaraj, Nithianandam, Drachman, David A, Ravin, Paula, Knorr, John R
Format: Article
Language:English
Subjects:
Alcohol
Angioplasty
Biological and medical sciences
Blood-brain barrier
Bupropion - adverse effects
Cardiovascular disease
Cardiovascular system
contrast media
Contrast Media - adverse effects
Diagnosis, Differential
Dopamine Uptake Inhibitors - adverse effects
Electroencephalography
Female
Heart attacks
Humans
Hypertension
Investigative techniques, diagnostic techniques (general aspects)
Medical imaging
Medical sciences
Middle Aged
myocardial infarction
Myocardial Infarction - etiology
Neurotoxicity
Radiodiagnosis. Nmr imagery. Nmr spectrometry
seizure
Seizures - chemically induced
Seizures - diagnostic imaging
Self-Assessment Questions
Subarachnoid Hemorrhage - diagnostic imaging
Tomography, X-Ray Computed - methods
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Summary:[...]it is unclear if this seizure was related to the history of seizures. Relative hypoxia due to increased ictal metabolism, with an increase in local pCO2 and lactate, results in local vasodilatation and loss of autoregulation. 5 Systemically there is an increase in blood pressure and decrease in blood pH, again resulting in decreased cerebral autoregulation and local hyperaemia. 6 It has also been reported that the degree of disruption of the BBB is proportional to the duration of seizure activity. Sage and colleagues have demonstrated increased permeability of the BBB after large intracarotid contrast injections. 7 Scott has previously reported that intravenous administration of contrast material for head CT may precipitate generalised seizures, especially in cases of metastatic neoplasm of the brain. 8 Neurologic complications after cardiac catheterisation are well known.
ISSN:0032-5473
1469-0756
DOI:10.1136/pgmj.75.890.757