A case of intestinal obstruction

[...]there have been reports of diaphragms complicating rectal indomethacin in the absence of oral preparations. 4 In such cases mucosal injury may be mediated via the systemic effects of NSAIDs on prostaglandin synthesis which results in increased mucosal permeability and translocation of luminal c...

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Bibliographic Details
Published in:Postgraduate medical journal 2000-03, Vol.76 (893), p.175-176
Main Authors: Michell, N P, Routledge, H, Chesner, I M
Format: Article
Language:English
Subjects:
Aged
Anti-Inflammatory Agents, Non-Steroidal - adverse effects
Biological and medical sciences
Bowel disease
Colonic Diseases - chemically induced
Crohn's disease
Diclofenac - adverse effects
Drug Combinations
Female
Gastroenterology. Liver. Pancreas. Abdomen
Humans
Inflammation
Intestinal Obstruction - chemically induced
Medical sciences
Other diseases. Semiology
Self-Assessment Questions
Stomach. Duodenum. Small intestine. Colon. Rectum. Anus
Sulfasalazine - adverse effects
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Description
Summary:[...]there have been reports of diaphragms complicating rectal indomethacin in the absence of oral preparations. 4 In such cases mucosal injury may be mediated via the systemic effects of NSAIDs on prostaglandin synthesis which results in increased mucosal permeability and translocation of luminal contents.
ISSN:0032-5473
1469-0756
DOI:10.1136/pmj.76.893.175