Metabolic alkalosis and myoclonus

This is the first case reported of vomiting-induced metabolic alkalosis associated with myoclonus. The report describes an unusual presentation of myoclonus secondary to acid-base disturbance caused by recreational drug-induced vomiting. The severe derangement of hyponatraemia, hypokalaemia, and alk...

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Bibliographic Details
Published in:Postgraduate medical journal 2003-07, Vol.79 (933), p.414-415
Main Authors: Simons, P, Nadra, I, McNally, P G
Format: Article
Language:English
Subjects:
Acid-Base Imbalance - etiology
Acids
Adult
Alkalosis
Alkalosis - etiology
Analgesics
Carbon dioxide
Care and treatment
Case Report
Causes of
Cocaine
Cocaine-Related Disorders - complications
Complications and side effects
Constipation
Diuretics
Drug abuse
Heroin Dependence - complications
Humans
hypokalaemia
hyponatraemia
Hypoxia
Laxatives
Male
metabolic alkalosis
Metabolism
Myoclonus
Myoclonus - etiology
Potassium
Street Drugs
Substance abuse treatment
Tumors
Urine
Vomiting
Vomiting - complications
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Summary:This is the first case reported of vomiting-induced metabolic alkalosis associated with myoclonus. The report describes an unusual presentation of myoclonus secondary to acid-base disturbance caused by recreational drug-induced vomiting. The severe derangement of hyponatraemia, hypokalaemia, and alkalosis appears to have been reasonably well tolerated due to the gradual onset and relatively long history. The causes, mechanism, and management of metabolic alkalosis are discussed.
ISSN:0032-5473
1469-0756
DOI:10.1136/pmj.79.933.414