Sodium cromoglycate in childhood asthma

Of the two trials which used the 5mg MDI, one was conducted in patients for whom the drug is not indicated-recurrent respiratory symptoms in preterm babies at a dose of 5mg three times daily using a coffee cup as a spacer- and the other was conducted by the authors of this paper in a general practic...

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Bibliographic Details
Published in:Thorax 2001-04, Vol.56 (4), p.331-331
Main Authors: EDWARDS, A, HOLGATE, S, HOWELL, J, WARNER, J, STEVENS, M, ÅBERG, N, CALLAGHAN, B, IIKURA, Y, KÖNIG, P, REINHARDT, D, STENIUS-AARNIALA, B, WEINBERG, E
Format: Article
Language:English
Subjects:
Administration, Inhalation
Adolescent
Age
Anti-Asthmatic Agents - administration & dosage
Asthma
Asthma - drug therapy
Child
Confidence intervals
Cromolyn Sodium - administration & dosage
Drug dosages
Humans
Letters to the Editor
Nebulizers and Vaporizers
Randomized Controlled Trials as Topic
Studies
Citations: Items that cite this one
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Summary:Of the two trials which used the 5mg MDI, one was conducted in patients for whom the drug is not indicated-recurrent respiratory symptoms in preterm babies at a dose of 5mg three times daily using a coffee cup as a spacer- and the other was conducted by the authors of this paper in a general practice setting in children aged 1-4 years and it has already been pointed out that the delivery system used may not have provided an adequate dose. 5 6 They also used less than the recommended dose (three times a day rather than four) and an incorrect dosing method (two puffs into the spacer for one inhalation). Common pitfalls of narrative reviews are that they tend to repeat the success stories of medical history but ignore negative studies, that they are authority based instead of evidence based, and authors of this type of review may have strong relations with pharmaceutical companies. 1-10-1-12 Our aim was not to give our personal opinion but to assess the benefits of SCG in asthmatic children in a systematic and unbiased way, without conflicts of interest.
ISSN:0040-6376
1468-3296
DOI:10.1136/thorax.56.4.331