The new front line treatment for malignant pleural mesothelioma?

[...]what was the rationale for the control arm? [...]the investigators concluded that pemetrexed with cisplatin, folic acid and vitamin B12 should be the "standard front line therapy" for patients with malignant pleural mesothelioma.

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Bibliographic Details
Published in:Thorax 2003-02, Vol.58 (2), p.96-97
Main Author: Steele, J P C
Format: Article
Language:English
Subjects:
Antineoplastic Combined Chemotherapy Protocols - therapeutic use
Cancer
Cancer therapies
Care and treatment
Chemotherapy
Cisplatin - administration & dosage
Cisplatin - therapeutic use
Clinical Trials, Phase III as Topic
Cytotoxicity
Drug dosages
Feasibility studies
Glutamates - administration & dosage
Guanine - administration & dosage
Guanine - analogs & derivatives
Humans
Medical research
Mesothelioma
Mesothelioma - drug therapy
Mortality
Multicenter Studies as Topic
Patient outcomes
Pemetrexed
Pleural Neoplasms - drug therapy
Quality of life
Randomized Controlled Trials as Topic
Researchers
Response rates
treatment
United Kingdom
Vitamin B
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Description
Summary:[...]what was the rationale for the control arm? [...]the investigators concluded that pemetrexed with cisplatin, folic acid and vitamin B12 should be the "standard front line therapy" for patients with malignant pleural mesothelioma.
ISSN:0040-6376
1468-3296
DOI:10.1136/thorax.58.2.96