CPAP suppression of awake right-to-left shunting through patent foramen ovale in a patient with obstructive sleep apnoea

The prevalence of an echocardiographically visible patent foramen ovale (PFO) is higher in patients with obstructive sleep apnoea syndrome (OSAS) than in normal controls. We report a patient who presented with OSAS and right-to-left shunting (RLS) through the PFO in whom the RLS disappeared after tr...

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Bibliographic Details
Published in:Thorax 2005-10, Vol.60 (10), p.880-881
Main Authors: Pinet, C, Orehek, J
Format: Article
Language:English
Subjects:
AHI
apnoea/hypopnoea index
Biological and medical sciences
Cardiology. Vascular system
Case Report
Chronic obstructive pulmonary disease
Congenital heart diseases. Malformations of the aorta, pulmonary vessels and vena cava
Continuous positive airway pressure
Continuous Positive Airway Pressure - methods
CPAP
Female
Heart
Heart Septal Defects, Atrial - therapy
Humans
Medical sciences
Middle Aged
obstructive sleep apnoea
obstructive sleep apnoea syndrome
OSAS
patent foramen ovale
Patients
PFO
Pneumology
Pulmonary hypertension
Pulmonary hypertension. Acute cor pulmonale. Pulmonary embolism. Pulmonary vascular diseases
Respiratory system : syndromes and miscellaneous diseases
right-to-left shunting
RLS
Sleep
Sleep Apnea, Obstructive - therapy
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Description
Summary:The prevalence of an echocardiographically visible patent foramen ovale (PFO) is higher in patients with obstructive sleep apnoea syndrome (OSAS) than in normal controls. We report a patient who presented with OSAS and right-to-left shunting (RLS) through the PFO in whom the RLS disappeared after treatment for 1 week with nocturnal continuous positive airway pressure (CPAP). This case shows the role of OSA in generating an awake RLS through a PFO and its possible reversibility by CPAP. The mechanism of reversible awake RLS through PFO in OSAS is discussed.
ISSN:0040-6376
1468-3296
DOI:10.1136/thx.2004.027508