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CPAP suppression of awake right-to-left shunting through patent foramen ovale in a patient with obstructive sleep apnoea
The prevalence of an echocardiographically visible patent foramen ovale (PFO) is higher in patients with obstructive sleep apnoea syndrome (OSAS) than in normal controls. We report a patient who presented with OSAS and right-to-left shunting (RLS) through the PFO in whom the RLS disappeared after tr...
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Published in: | Thorax 2005-10, Vol.60 (10), p.880-881 |
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description | The prevalence of an echocardiographically visible patent foramen ovale (PFO) is higher in patients with obstructive sleep apnoea syndrome (OSAS) than in normal controls. We report a patient who presented with OSAS and right-to-left shunting (RLS) through the PFO in whom the RLS disappeared after treatment for 1 week with nocturnal continuous positive airway pressure (CPAP). This case shows the role of OSA in generating an awake RLS through a PFO and its possible reversibility by CPAP. The mechanism of reversible awake RLS through PFO in OSAS is discussed. |
doi_str_mv | 10.1136/thx.2004.027508 |
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We report a patient who presented with OSAS and right-to-left shunting (RLS) through the PFO in whom the RLS disappeared after treatment for 1 week with nocturnal continuous positive airway pressure (CPAP). This case shows the role of OSA in generating an awake RLS through a PFO and its possible reversibility by CPAP. The mechanism of reversible awake RLS through PFO in OSAS is discussed.</description><identifier>ISSN: 0040-6376</identifier><identifier>EISSN: 1468-3296</identifier><identifier>DOI: 10.1136/thx.2004.027508</identifier><identifier>PMID: 16192368</identifier><identifier>CODEN: THORA7</identifier><language>eng</language><publisher>London: BMJ Publishing Group Ltd and British Thoracic Society</publisher><subject>AHI ; apnoea/hypopnoea index ; Biological and medical sciences ; Cardiology. Vascular system ; Case Report ; Chronic obstructive pulmonary disease ; Congenital heart diseases. Malformations of the aorta, pulmonary vessels and vena cava ; Continuous positive airway pressure ; Continuous Positive Airway Pressure - methods ; CPAP ; Female ; Heart ; Heart Septal Defects, Atrial - therapy ; Humans ; Medical sciences ; Middle Aged ; obstructive sleep apnoea ; obstructive sleep apnoea syndrome ; OSAS ; patent foramen ovale ; Patients ; PFO ; Pneumology ; Pulmonary hypertension ; Pulmonary hypertension. Acute cor pulmonale. Pulmonary embolism. Pulmonary vascular diseases ; Respiratory system : syndromes and miscellaneous diseases ; right-to-left shunting ; RLS ; Sleep ; Sleep Apnea, Obstructive - therapy</subject><ispartof>Thorax, 2005-10, Vol.60 (10), p.880-881</ispartof><rights>Copyright 2005 Thorax</rights><rights>2005 INIST-CNRS</rights><rights>Copyright: 2005 Copyright 2005 Thorax</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-b522t-7e250c1def970a3e3be2240eb7d3742ef5af6aed675ae37eab906264b1c231143</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC1747216/pdf/$$EPDF$$P50$$Gpubmedcentral$$H</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC1747216/$$EHTML$$P50$$Gpubmedcentral$$H</linktohtml><link.rule.ids>230,314,727,780,784,885,27923,27924,53790,53792</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=17193367$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/16192368$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Pinet, C</creatorcontrib><creatorcontrib>Orehek, J</creatorcontrib><title>CPAP suppression of awake right-to-left shunting through patent foramen ovale in a patient with obstructive sleep apnoea</title><title>Thorax</title><addtitle>Thorax</addtitle><description>The prevalence of an echocardiographically visible patent foramen ovale (PFO) is higher in patients with obstructive sleep apnoea syndrome (OSAS) than in normal controls. We report a patient who presented with OSAS and right-to-left shunting (RLS) through the PFO in whom the RLS disappeared after treatment for 1 week with nocturnal continuous positive airway pressure (CPAP). This case shows the role of OSA in generating an awake RLS through a PFO and its possible reversibility by CPAP. The mechanism of reversible awake RLS through PFO in OSAS is discussed.</description><subject>AHI</subject><subject>apnoea/hypopnoea index</subject><subject>Biological and medical sciences</subject><subject>Cardiology. Vascular system</subject><subject>Case Report</subject><subject>Chronic obstructive pulmonary disease</subject><subject>Congenital heart diseases. Malformations of the aorta, pulmonary vessels and vena cava</subject><subject>Continuous positive airway pressure</subject><subject>Continuous Positive Airway Pressure - methods</subject><subject>CPAP</subject><subject>Female</subject><subject>Heart</subject><subject>Heart Septal Defects, Atrial - therapy</subject><subject>Humans</subject><subject>Medical sciences</subject><subject>Middle Aged</subject><subject>obstructive sleep apnoea</subject><subject>obstructive sleep apnoea syndrome</subject><subject>OSAS</subject><subject>patent foramen ovale</subject><subject>Patients</subject><subject>PFO</subject><subject>Pneumology</subject><subject>Pulmonary hypertension</subject><subject>Pulmonary hypertension. Acute cor pulmonale. Pulmonary embolism. Pulmonary vascular diseases</subject><subject>Respiratory system : syndromes and miscellaneous diseases</subject><subject>right-to-left shunting</subject><subject>RLS</subject><subject>Sleep</subject><subject>Sleep Apnea, Obstructive - therapy</subject><issn>0040-6376</issn><issn>1468-3296</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2005</creationdate><recordtype>article</recordtype><recordid>eNqFkU1v00AQhi0EoqFw5oZWQnBAcrof9q59qVQivitIxcd1NXbG8aaO1-yu0_DvWStRC1w4zeF55tWM3iR5yuicMSHPQrufc0qzOeUqp8W9ZMYyWaSCl_J-MouAplIoeZI88n5DKS0YUw-TEyZZyYUsZsl-sbxYEj8Og0Pvje2JbQjcwDUSZ9ZtSINNO2wC8e3YB9OvSWidHdctGSBgH0hjHWwxru2gQ2J6AhMxE7oxoSW28sGNdTA7JL5DHAgMvUV4nDxooPP45DhPk-9v33xbvE8vv7z7sLi4TKuc85Aq5Dmt2QqbUlEQKCrkPKNYqZVQGccmh0YCrqTKAYVCqEoqucwqVnPBWCZOk_ND7jBWW1zV8TAHnR6c2YL7pS0Y_TfpTavXdqeZyhRnMga8PAY4-3NEH_TW-Bq7Dnq0o9eykEJmeRHF5_-IGzu6Pj4XswqmJFXlZJ0drNpZ7x02t6cwqqdOdexUT53qQ6dx49mfH9z5xxKj8OIogK-haxz0tfF3nmKlEFJFLz14xgfc33Jw1zpSlevPPxb66uNV-fX1p1Ivo__q4FfbzX-v_A0vhskp</recordid><startdate>20051001</startdate><enddate>20051001</enddate><creator>Pinet, C</creator><creator>Orehek, J</creator><general>BMJ Publishing Group Ltd and British Thoracic Society</general><general>BMJ</general><general>BMJ Publishing Group LTD</general><general>BMJ Group</general><scope>BSCLL</scope><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>BENPR</scope><scope>BTHHO</scope><scope>CCPQU</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>K9.</scope><scope>M0S</scope><scope>M1P</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>7X8</scope><scope>5PM</scope></search><sort><creationdate>20051001</creationdate><title>CPAP suppression of awake right-to-left shunting through patent foramen ovale in a patient with obstructive sleep apnoea</title><author>Pinet, C ; Orehek, J</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-b522t-7e250c1def970a3e3be2240eb7d3742ef5af6aed675ae37eab906264b1c231143</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2005</creationdate><topic>AHI</topic><topic>apnoea/hypopnoea index</topic><topic>Biological and medical sciences</topic><topic>Cardiology. Vascular system</topic><topic>Case Report</topic><topic>Chronic obstructive pulmonary disease</topic><topic>Congenital heart diseases. Malformations of the aorta, pulmonary vessels and vena cava</topic><topic>Continuous positive airway pressure</topic><topic>Continuous Positive Airway Pressure - methods</topic><topic>CPAP</topic><topic>Female</topic><topic>Heart</topic><topic>Heart Septal Defects, Atrial - therapy</topic><topic>Humans</topic><topic>Medical sciences</topic><topic>Middle Aged</topic><topic>obstructive sleep apnoea</topic><topic>obstructive sleep apnoea syndrome</topic><topic>OSAS</topic><topic>patent foramen ovale</topic><topic>Patients</topic><topic>PFO</topic><topic>Pneumology</topic><topic>Pulmonary hypertension</topic><topic>Pulmonary hypertension. Acute cor pulmonale. Pulmonary embolism. Pulmonary vascular diseases</topic><topic>Respiratory system : syndromes and miscellaneous diseases</topic><topic>right-to-left shunting</topic><topic>RLS</topic><topic>Sleep</topic><topic>Sleep Apnea, Obstructive - therapy</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Pinet, C</creatorcontrib><creatorcontrib>Orehek, J</creatorcontrib><collection>Istex</collection><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni)</collection><collection>ProQuest Central</collection><collection>ProQuest Central</collection><collection>BMJ Journals</collection><collection>ProQuest One Community College</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>PML(ProQuest Medical Library)</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Thorax</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Pinet, C</au><au>Orehek, J</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>CPAP suppression of awake right-to-left shunting through patent foramen ovale in a patient with obstructive sleep apnoea</atitle><jtitle>Thorax</jtitle><addtitle>Thorax</addtitle><date>2005-10-01</date><risdate>2005</risdate><volume>60</volume><issue>10</issue><spage>880</spage><epage>881</epage><pages>880-881</pages><issn>0040-6376</issn><eissn>1468-3296</eissn><coden>THORA7</coden><abstract>The prevalence of an echocardiographically visible patent foramen ovale (PFO) is higher in patients with obstructive sleep apnoea syndrome (OSAS) than in normal controls. We report a patient who presented with OSAS and right-to-left shunting (RLS) through the PFO in whom the RLS disappeared after treatment for 1 week with nocturnal continuous positive airway pressure (CPAP). This case shows the role of OSA in generating an awake RLS through a PFO and its possible reversibility by CPAP. The mechanism of reversible awake RLS through PFO in OSAS is discussed.</abstract><cop>London</cop><pub>BMJ Publishing Group Ltd and British Thoracic Society</pub><pmid>16192368</pmid><doi>10.1136/thx.2004.027508</doi><tpages>2</tpages><oa>free_for_read</oa></addata></record> |
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subjects | AHI apnoea/hypopnoea index Biological and medical sciences Cardiology. Vascular system Case Report Chronic obstructive pulmonary disease Congenital heart diseases. Malformations of the aorta, pulmonary vessels and vena cava Continuous positive airway pressure Continuous Positive Airway Pressure - methods CPAP Female Heart Heart Septal Defects, Atrial - therapy Humans Medical sciences Middle Aged obstructive sleep apnoea obstructive sleep apnoea syndrome OSAS patent foramen ovale Patients PFO Pneumology Pulmonary hypertension Pulmonary hypertension. Acute cor pulmonale. Pulmonary embolism. Pulmonary vascular diseases Respiratory system : syndromes and miscellaneous diseases right-to-left shunting RLS Sleep Sleep Apnea, Obstructive - therapy |
title | CPAP suppression of awake right-to-left shunting through patent foramen ovale in a patient with obstructive sleep apnoea |
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