Pulmonary function tests and high resolution computed tomography of the lungs in patients with rheumatoid arthritis

OBJECTIVE To compare the results of pulmonary function tests (PFTs) and high resolution computed tomography (HRCT) of the lungs in rheumatoid arthritis (RA) patients. METHODS Sixty eight patients (54 women, 14 men) fulfilling the revised criteria for RA were consecutively included in a transversal p...

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Bibliographic Details
Published in:Annals of the rheumatic diseases 1997-10, Vol.56 (10), p.596-600
Main Authors: Cortet, Bernard, Perez, Thierry, Roux, Nicolas, Flipo, René-Marc, Duquesnoy, Bernard, Delcambre, Bernard, Rémy-Jardin, Martine
Format: Article
Language:English
Subjects:
Adult
Aged
Aged, 80 and over
Arthritis, Rheumatoid - complications
Arthritis, Rheumatoid - diagnostic imaging
Arthritis, Rheumatoid - physiopathology
Biological and medical sciences
bronchiectasis
Bronchiectasis - complications
Bronchiectasis - diagnostic imaging
Bronchiectasis - physiopathology
Bronchitis - complications
Bronchitis - diagnostic imaging
Bronchitis - physiopathology
Diseases of the osteoarticular system
Extended Reports
Female
high resolution computed tomography
Humans
Inflammatory joint diseases
Lung - diagnostic imaging
Lung - physiopathology
Lung diseases
Lungs
Male
Medical sciences
Middle Aged
Prospective Studies
pulmonary function tests
Respiratory Function Tests
Rheumatoid arthritis
Smoking - physiopathology
Tomography
Tomography, X-Ray Computed
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Summary:OBJECTIVE To compare the results of pulmonary function tests (PFTs) and high resolution computed tomography (HRCT) of the lungs in rheumatoid arthritis (RA) patients. METHODS Sixty eight patients (54 women, 14 men) fulfilling the revised criteria for RA were consecutively included in a transversal prospective study. Their mean age was 58.8 years (range: 35–82) and the mean duration of the disease was 12 years (range: 5–16). Rheumatoid factor was positive in 52 patients (76.5%). Fifty two patients (76.5%) were lifelong non-smokers. Detailed medical and drug histories were obtained. PFTs comprised spirometry and gas transfer measurements. Results for PFTs were expressed as percentage of predicted values for each individual adjusted for age, sex, and height. HRCT was undertaken with a Siemens Somatom Plus. RESULTS A significant decrease of FEV1/FVC, FEF25%, FEF50%, FEF75%, FEF25–75%, and TLCO was observed (p
ISSN:0003-4967
1468-2060
DOI:10.1136/ard.56.10.596