Treatment of oral dryness related complaints (xerostomia) in Sjögren’s syndrome

Other common causes of prolonged hyposalivation include other autoimmune disorders such as systemic lupus erythematosus, 22 23 uncontrolled diabetes mellitus 24 25 and salivary gland injury as a result of radiotherapy in the head and neck region. 26 This review describes the current treatments with...

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Bibliographic Details
Published in:Annals of the rheumatic diseases 1999-08, Vol.58 (8), p.465-473
Main Authors: van der Reijden, Willy A, Vissink, Arjan, Veerman, Enno C I, Amerongen, Arie V Nieuw
Format: Article
Language:English
Subjects:
Autoimmune diseases
Biological and medical sciences
Complaints
Disease
Forecasting
Humans
Lupus
Lymphocytes
Medical sciences
Mouth Diseases - therapy
Opportunistic Infections - therapy
Peptides
Proteins
Review
Saliva, Artificial - therapeutic use
Salivation
Sarcoidosis. Granulomatous diseases of unproved etiology. Connective tissue diseases. Elastic tissue diseases. Vasculitis
Sjogren's Syndrome - complications
T cell receptors
Xerostomia - etiology
Xerostomia - therapy
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Summary:Other common causes of prolonged hyposalivation include other autoimmune disorders such as systemic lupus erythematosus, 22 23 uncontrolled diabetes mellitus 24 25 and salivary gland injury as a result of radiotherapy in the head and neck region. 26 This review describes the current treatments with regard to xerostomia focused on patients with SS. Because the treatment of the cause of oral dryness in Sjögren patients is possible so far, treatment is focused on stimulation of the residual capacity of the salivary glands and/or substitution of saliva with mouth rinses or saliva substitutes if stimulation of residual secretory capacity produces a too small effect.
ISSN:0003-4967
1468-2060
DOI:10.1136/ard.58.8.465