Rheumatological complications associated with the use of indinavir and other protease inhibitors

Several cases are reported of rheumatological pathology (temporomandibular dysfunction, frozen shoulder, Dupuytren's disease, and tendinitis) most probably related to the intake of indinavir in HIV positive patients. A survey using an anonymous questionnaire of 878 people with HIV infection tre...

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Bibliographic Details
Published in:Annals of the rheumatic diseases 2002-01, Vol.61 (1), p.82-84
Main Authors: Florence, E, Schrooten, W, Verdonck, K, Dreezen, C, Colebunders, R
Format: Article
Language:English
Subjects:
Adult
Antiretroviral drugs
Arthralgia
arthritis
Biological and medical sciences
Causes of
Complications and side effects
Concise Report
Disease
Drug therapy
Drug toxicity and drugs side effects treatment
Dupuytren Contracture - chemically induced
Female
frozen shoulder
Hair loss
HIV
HIV infection
HIV Infections - drug therapy
HIV Protease Inhibitors - adverse effects
Human immunodeficiency virus
Humans
Indinavir
Indinavir - adverse effects
Infections
Lymphocytes
Male
Medical sciences
Middle Aged
Multivariate analysis
Pharmacology. Drug treatments
protease inhibitor indinavir
Protease inhibitors
Rheumatic Diseases - chemically induced
Shoulder
Shoulder Impingement Syndrome - chemically induced
Substance abuse treatment
Temporomandibular Joint Dysfunction Syndrome - chemically induced
Tendinopathy - chemically induced
Toxicity: osteoarticular system
Citations: Items that cite this one
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Description
Summary:Several cases are reported of rheumatological pathology (temporomandibular dysfunction, frozen shoulder, Dupuytren's disease, and tendinitis) most probably related to the intake of indinavir in HIV positive patients. A survey using an anonymous questionnaire of 878 people with HIV infection treated with antiretroviral drugs suggests that other protease inhibitors may also cause arthralgia.
ISSN:0003-4967
1468-2060
DOI:10.1136/ard.61.1.82