Risk factors for accelerated atherosclerosis in patients with systemic lupus erythematosus

Patients with plaque or abnormal IMT were significantly older (mean (SD) 69 (7) v 39 (12) years or 62 (14) v 39 (14) years, p140/90 mm Hg or treatment with antihypertensive drugs) was also more common in plaque positive (67%) than in plaque negative (7%) patients (p = 0.0001). [...]among traditional...

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Bibliographic Details
Published in:Annals of the rheumatic diseases 2005-01, Vol.64 (1), p.163-164
Main Authors: Marasini, B, De Monti, M, Ghilardi, G
Format: Article
Language:English
Subjects:
Adult
Aged
Arteriosclerosis - etiology
Atherosclerosis
Atherosclerosis (general aspects, experimental research)
atherosclerotic plaque
Biological and medical sciences
Blood and lymphatic vessels
Blood pressure
Cardiology. Vascular system
Disease
Female
Health risk assessment
Humans
intimal medial thickness
Letter
Lupus
Lupus Erythematosus, Systemic - complications
Male
Medical sciences
Middle Aged
Mortality
Risk Factors
Sarcoidosis. Granulomatous diseases of unproved etiology. Connective tissue diseases. Elastic tissue diseases. Vasculitis
systemic lupus erythematosus
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Summary:Patients with plaque or abnormal IMT were significantly older (mean (SD) 69 (7) v 39 (12) years or 62 (14) v 39 (14) years, p140/90 mm Hg or treatment with antihypertensive drugs) was also more common in plaque positive (67%) than in plaque negative (7%) patients (p = 0.0001). [...]among traditional risk factors, we found that men with SLE tended to have plaque more often (20%) than women with SLE (12%), in accord with recent observations both on patients with SLE and the general population. 4, 7 We did not find any relationship between carotid abnormalities, cumulative prednisone intake, or inflammation markers (erythrocyte sedimentation rate, fibrinogen, and C reactive protein).
ISSN:0003-4967
1468-2060
DOI:10.1136/ard.2004.024299