Enduring increased risk of developing depression and mania in patients with dementia

Objective: To investigate the time relation between dementia and major affective disorders (major depression and mania). Methods: Register linkage study of the Danish Hospital Register and the Danish Psychiatric Central Research Register, to establish study cohorts of patients with dementia and cont...

Full description

Saved in:
Bibliographic Details
Published in:Journal of neurology, neurosurgery and psychiatry neurosurgery and psychiatry, 2002-07, Vol.73 (1), p.40-44
Main Authors: Nilsson, F M, Kessing, L V, Sørensen, T M, Andersen, P K, Bolwig, T G
Format: Article
Language:English
Subjects:
affective disorder
Aged
Aged, 80 and over
Biological and medical sciences
Bipolar Disorder - etiology
Cohort Studies
Complications and side effects
Danish National Hospital Register
Danish Psychiatric Central Register
Dementia
Dementia - psychology
Depression - etiology
Depression, Mental
Development and progression
DNHR
DPCR
Female
Humans
Male
Medical sciences
Middle Aged
Nervous system (semeiology, syndromes)
Nervous system as a whole
Neurology
Poisson Distribution
Research Design
Risk
survival analysis
Time Factors
Citations: Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
cited_by cdi_FETCH-LOGICAL-b583t-15a68bf35d50af2e79c39fae40445e5fce384ebf34f0ac94c4ef415b7b558fd93
cites
container_end_page 44
container_issue 1
container_start_page 40
container_title Journal of neurology, neurosurgery and psychiatry
container_volume 73
creator Nilsson, F M
Kessing, L V
Sørensen, T M
Andersen, P K
Bolwig, T G
description Objective: To investigate the time relation between dementia and major affective disorders (major depression and mania). Methods: Register linkage study of the Danish Hospital Register and the Danish Psychiatric Central Research Register, to establish study cohorts of patients with dementia and control groups (osteoarthritis or diabetes) on first discharge from hospital. Follow up of cohorts was for up to 21 years. Hazard of death was allowed for by the use of competing risks models. Results: Patients with dementia had an increased risk of being admitted to hospital for major depression or mania during the course of the illness. The incidence remained elevated throughout the rest of the patient's life. Conclusions: Patients with dementia have an increased risk of developing depression or mania. Proper treatment of affective disorders in patients with dementia is important in reducing suffering and costs.
doi_str_mv 10.1136/jnnp.73.1.40
format article
fullrecord <record><control><sourceid>gale_pubme</sourceid><recordid>TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_1757324</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><galeid>A89146385</galeid><sourcerecordid>A89146385</sourcerecordid><originalsourceid>FETCH-LOGICAL-b583t-15a68bf35d50af2e79c39fae40445e5fce384ebf34f0ac94c4ef415b7b558fd93</originalsourceid><addsrcrecordid>eNp9ks2P1CAYh4nRuOPozbNpYtSLHaHAlF422cyursn6cViNN0LpyyyzLVRoV_3vpZlmR81GOBB4H37vJ0JPCV4RQtdvds71q5KuyIrhe2hB2FrklOJv99EC46LIKeb4CD2KcYenJaqH6IgUWBSY0QW6PHPNGKzbZtbpACpCkwUbrzNvsgZuoPX9ZGygDxCj9S5Trsk65axKP7JeDRbcELMfdrhKVJcuVj1GD4xqIzyZzyX68vbscnOeX3x6935zcpHXXNAhJ1ytRW0obzhWpoCy0rQyChhmjAM3GqhgkABmsNIV0wwMI7wua86FaSq6RMd73X6sO2h0ch5UK_tgOxV-Sa-s_Nvi7JXc-htJSl7SgiWBl7NA8N9HiIPsbNTQtsqBH6MsieC0EEUCn_8D7vwYXEouaQnCC0z5RL3eU1vVgrTO-ORVb8FBcu4dGJueT0SVekST8BLld-BppzpafRc_y-vgYwxgbjMlWE6zIKdZkCWVRDKc8Gd_VucAz81PwIsZUFGr1gTltI0Hjpa0rDA7xGnjAD9v7Spcy3VCuPz4dSM_nOMNr04_y9PEv9rzdbf7f4i_Aana2e0</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1781520352</pqid></control><display><type>article</type><title>Enduring increased risk of developing depression and mania in patients with dementia</title><source>Open Access: PubMed Central</source><creator>Nilsson, F M ; Kessing, L V ; Sørensen, T M ; Andersen, P K ; Bolwig, T G</creator><creatorcontrib>Nilsson, F M ; Kessing, L V ; Sørensen, T M ; Andersen, P K ; Bolwig, T G</creatorcontrib><description>Objective: To investigate the time relation between dementia and major affective disorders (major depression and mania). Methods: Register linkage study of the Danish Hospital Register and the Danish Psychiatric Central Research Register, to establish study cohorts of patients with dementia and control groups (osteoarthritis or diabetes) on first discharge from hospital. Follow up of cohorts was for up to 21 years. Hazard of death was allowed for by the use of competing risks models. Results: Patients with dementia had an increased risk of being admitted to hospital for major depression or mania during the course of the illness. The incidence remained elevated throughout the rest of the patient's life. Conclusions: Patients with dementia have an increased risk of developing depression or mania. Proper treatment of affective disorders in patients with dementia is important in reducing suffering and costs.</description><identifier>ISSN: 0022-3050</identifier><identifier>EISSN: 1468-330X</identifier><identifier>DOI: 10.1136/jnnp.73.1.40</identifier><identifier>PMID: 12082043</identifier><identifier>CODEN: JNNPAU</identifier><language>eng</language><publisher>London: BMJ Publishing Group Ltd</publisher><subject>affective disorder ; Aged ; Aged, 80 and over ; Biological and medical sciences ; Bipolar Disorder - etiology ; Cohort Studies ; Complications and side effects ; Danish National Hospital Register ; Danish Psychiatric Central Register ; Dementia ; Dementia - psychology ; Depression - etiology ; Depression, Mental ; Development and progression ; DNHR ; DPCR ; Female ; Humans ; Male ; Medical sciences ; Middle Aged ; Nervous system (semeiology, syndromes) ; Nervous system as a whole ; Neurology ; Poisson Distribution ; Research Design ; Risk ; survival analysis ; Time Factors</subject><ispartof>Journal of neurology, neurosurgery and psychiatry, 2002-07, Vol.73 (1), p.40-44</ispartof><rights>Copyright 2002 Journal of Neurology Neurosurgery and Psychiatry</rights><rights>2002 INIST-CNRS</rights><rights>COPYRIGHT 2002 BMJ Publishing Group Ltd.</rights><rights>Copyright: 2002 Copyright 2002 Journal of Neurology Neurosurgery and Psychiatry</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-b583t-15a68bf35d50af2e79c39fae40445e5fce384ebf34f0ac94c4ef415b7b558fd93</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC1757324/pdf/$$EPDF$$P50$$Gpubmedcentral$$H</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC1757324/$$EHTML$$P50$$Gpubmedcentral$$H</linktohtml><link.rule.ids>230,314,727,780,784,885,27924,27925,53791,53793</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&amp;idt=13737904$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/12082043$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Nilsson, F M</creatorcontrib><creatorcontrib>Kessing, L V</creatorcontrib><creatorcontrib>Sørensen, T M</creatorcontrib><creatorcontrib>Andersen, P K</creatorcontrib><creatorcontrib>Bolwig, T G</creatorcontrib><title>Enduring increased risk of developing depression and mania in patients with dementia</title><title>Journal of neurology, neurosurgery and psychiatry</title><addtitle>J Neurol Neurosurg Psychiatry</addtitle><description>Objective: To investigate the time relation between dementia and major affective disorders (major depression and mania). Methods: Register linkage study of the Danish Hospital Register and the Danish Psychiatric Central Research Register, to establish study cohorts of patients with dementia and control groups (osteoarthritis or diabetes) on first discharge from hospital. Follow up of cohorts was for up to 21 years. Hazard of death was allowed for by the use of competing risks models. Results: Patients with dementia had an increased risk of being admitted to hospital for major depression or mania during the course of the illness. The incidence remained elevated throughout the rest of the patient's life. Conclusions: Patients with dementia have an increased risk of developing depression or mania. Proper treatment of affective disorders in patients with dementia is important in reducing suffering and costs.</description><subject>affective disorder</subject><subject>Aged</subject><subject>Aged, 80 and over</subject><subject>Biological and medical sciences</subject><subject>Bipolar Disorder - etiology</subject><subject>Cohort Studies</subject><subject>Complications and side effects</subject><subject>Danish National Hospital Register</subject><subject>Danish Psychiatric Central Register</subject><subject>Dementia</subject><subject>Dementia - psychology</subject><subject>Depression - etiology</subject><subject>Depression, Mental</subject><subject>Development and progression</subject><subject>DNHR</subject><subject>DPCR</subject><subject>Female</subject><subject>Humans</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Middle Aged</subject><subject>Nervous system (semeiology, syndromes)</subject><subject>Nervous system as a whole</subject><subject>Neurology</subject><subject>Poisson Distribution</subject><subject>Research Design</subject><subject>Risk</subject><subject>survival analysis</subject><subject>Time Factors</subject><issn>0022-3050</issn><issn>1468-330X</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2002</creationdate><recordtype>article</recordtype><recordid>eNp9ks2P1CAYh4nRuOPozbNpYtSLHaHAlF422cyursn6cViNN0LpyyyzLVRoV_3vpZlmR81GOBB4H37vJ0JPCV4RQtdvds71q5KuyIrhe2hB2FrklOJv99EC46LIKeb4CD2KcYenJaqH6IgUWBSY0QW6PHPNGKzbZtbpACpCkwUbrzNvsgZuoPX9ZGygDxCj9S5Trsk65axKP7JeDRbcELMfdrhKVJcuVj1GD4xqIzyZzyX68vbscnOeX3x6935zcpHXXNAhJ1ytRW0obzhWpoCy0rQyChhmjAM3GqhgkABmsNIV0wwMI7wua86FaSq6RMd73X6sO2h0ch5UK_tgOxV-Sa-s_Nvi7JXc-htJSl7SgiWBl7NA8N9HiIPsbNTQtsqBH6MsieC0EEUCn_8D7vwYXEouaQnCC0z5RL3eU1vVgrTO-ORVb8FBcu4dGJueT0SVekST8BLld-BppzpafRc_y-vgYwxgbjMlWE6zIKdZkCWVRDKc8Gd_VucAz81PwIsZUFGr1gTltI0Hjpa0rDA7xGnjAD9v7Spcy3VCuPz4dSM_nOMNr04_y9PEv9rzdbf7f4i_Aana2e0</recordid><startdate>20020701</startdate><enddate>20020701</enddate><creator>Nilsson, F M</creator><creator>Kessing, L V</creator><creator>Sørensen, T M</creator><creator>Andersen, P K</creator><creator>Bolwig, T G</creator><general>BMJ Publishing Group Ltd</general><general>BMJ</general><general>BMJ Publishing Group LTD</general><general>BMJ Group</general><scope>BSCLL</scope><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7RV</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>88G</scope><scope>88I</scope><scope>8AF</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>BTHHO</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>HCIFZ</scope><scope>K9.</scope><scope>KB0</scope><scope>M0S</scope><scope>M1P</scope><scope>M2M</scope><scope>M2P</scope><scope>NAPCQ</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>PSYQQ</scope><scope>Q9U</scope><scope>7X8</scope><scope>5PM</scope></search><sort><creationdate>20020701</creationdate><title>Enduring increased risk of developing depression and mania in patients with dementia</title><author>Nilsson, F M ; Kessing, L V ; Sørensen, T M ; Andersen, P K ; Bolwig, T G</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-b583t-15a68bf35d50af2e79c39fae40445e5fce384ebf34f0ac94c4ef415b7b558fd93</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2002</creationdate><topic>affective disorder</topic><topic>Aged</topic><topic>Aged, 80 and over</topic><topic>Biological and medical sciences</topic><topic>Bipolar Disorder - etiology</topic><topic>Cohort Studies</topic><topic>Complications and side effects</topic><topic>Danish National Hospital Register</topic><topic>Danish Psychiatric Central Register</topic><topic>Dementia</topic><topic>Dementia - psychology</topic><topic>Depression - etiology</topic><topic>Depression, Mental</topic><topic>Development and progression</topic><topic>DNHR</topic><topic>DPCR</topic><topic>Female</topic><topic>Humans</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Middle Aged</topic><topic>Nervous system (semeiology, syndromes)</topic><topic>Nervous system as a whole</topic><topic>Neurology</topic><topic>Poisson Distribution</topic><topic>Research Design</topic><topic>Risk</topic><topic>survival analysis</topic><topic>Time Factors</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Nilsson, F M</creatorcontrib><creatorcontrib>Kessing, L V</creatorcontrib><creatorcontrib>Sørensen, T M</creatorcontrib><creatorcontrib>Andersen, P K</creatorcontrib><creatorcontrib>Bolwig, T G</creatorcontrib><collection>Istex</collection><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>ProQuest Nursing and Allied Health Journals</collection><collection>Health &amp; Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>Psychology Database (Alumni)</collection><collection>Science Database (Alumni Edition)</collection><collection>STEM Database</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central Essentials</collection><collection>AUTh Library subscriptions: ProQuest Central</collection><collection>BMJ Journals</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>SciTech Premium Collection</collection><collection>ProQuest Health &amp; Medical Complete (Alumni)</collection><collection>Nursing &amp; Allied Health Database (Alumni Edition)</collection><collection>Health &amp; Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Psychology Database</collection><collection>ProQuest Science Journals</collection><collection>Nursing &amp; Allied Health Premium</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>ProQuest One Psychology</collection><collection>ProQuest Central Basic</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Journal of neurology, neurosurgery and psychiatry</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Nilsson, F M</au><au>Kessing, L V</au><au>Sørensen, T M</au><au>Andersen, P K</au><au>Bolwig, T G</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Enduring increased risk of developing depression and mania in patients with dementia</atitle><jtitle>Journal of neurology, neurosurgery and psychiatry</jtitle><addtitle>J Neurol Neurosurg Psychiatry</addtitle><date>2002-07-01</date><risdate>2002</risdate><volume>73</volume><issue>1</issue><spage>40</spage><epage>44</epage><pages>40-44</pages><issn>0022-3050</issn><eissn>1468-330X</eissn><coden>JNNPAU</coden><abstract>Objective: To investigate the time relation between dementia and major affective disorders (major depression and mania). Methods: Register linkage study of the Danish Hospital Register and the Danish Psychiatric Central Research Register, to establish study cohorts of patients with dementia and control groups (osteoarthritis or diabetes) on first discharge from hospital. Follow up of cohorts was for up to 21 years. Hazard of death was allowed for by the use of competing risks models. Results: Patients with dementia had an increased risk of being admitted to hospital for major depression or mania during the course of the illness. The incidence remained elevated throughout the rest of the patient's life. Conclusions: Patients with dementia have an increased risk of developing depression or mania. Proper treatment of affective disorders in patients with dementia is important in reducing suffering and costs.</abstract><cop>London</cop><pub>BMJ Publishing Group Ltd</pub><pmid>12082043</pmid><doi>10.1136/jnnp.73.1.40</doi><tpages>5</tpages><oa>free_for_read</oa></addata></record>
fulltext fulltext
identifier ISSN: 0022-3050
ispartof Journal of neurology, neurosurgery and psychiatry, 2002-07, Vol.73 (1), p.40-44
issn 0022-3050
1468-330X
language eng
recordid cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_1757324
source Open Access: PubMed Central
subjects affective disorder
Aged
Aged, 80 and over
Biological and medical sciences
Bipolar Disorder - etiology
Cohort Studies
Complications and side effects
Danish National Hospital Register
Danish Psychiatric Central Register
Dementia
Dementia - psychology
Depression - etiology
Depression, Mental
Development and progression
DNHR
DPCR
Female
Humans
Male
Medical sciences
Middle Aged
Nervous system (semeiology, syndromes)
Nervous system as a whole
Neurology
Poisson Distribution
Research Design
Risk
survival analysis
Time Factors
title Enduring increased risk of developing depression and mania in patients with dementia
url http://sfxeu10.hosted.exlibrisgroup.com/loughborough?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-28T15%3A28%3A07IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-gale_pubme&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Enduring%20increased%20risk%20of%20developing%20depression%20and%20mania%20in%20patients%20with%20dementia&rft.jtitle=Journal%20of%20neurology,%20neurosurgery%20and%20psychiatry&rft.au=Nilsson,%20F%20M&rft.date=2002-07-01&rft.volume=73&rft.issue=1&rft.spage=40&rft.epage=44&rft.pages=40-44&rft.issn=0022-3050&rft.eissn=1468-330X&rft.coden=JNNPAU&rft_id=info:doi/10.1136/jnnp.73.1.40&rft_dat=%3Cgale_pubme%3EA89146385%3C/gale_pubme%3E%3Cgrp_id%3Ecdi_FETCH-LOGICAL-b583t-15a68bf35d50af2e79c39fae40445e5fce384ebf34f0ac94c4ef415b7b558fd93%3C/grp_id%3E%3Coa%3E%3C/oa%3E%3Curl%3E%3C/url%3E&rft_id=info:oai/&rft_pqid=1781520352&rft_id=info:pmid/12082043&rft_galeid=A89146385&rfr_iscdi=true