Brain lesions in the course of generalised tetanus

A 47 year old woman developed left hemiparesis primarily affecting the lower limbs during the course of severe generalised tetanus. MRI on the 82nd hospital day revealed cortical and subcortical lesions predominantly in the right frontal and parietal lobes in addition to marked brain atrophy. Three...

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Bibliographic Details
Published in:Journal of neurology, neurosurgery and psychiatry neurosurgery and psychiatry, 2003-10, Vol.74 (10), p.1432-1434
Main Authors: Ijichi, T, Yamada, T, Yoneda, S, Kajita, Y, Nakajima, K, Nakagawa, M
Format: Article
Language:English
Subjects:
Abnormalities
Anesthesia
Atrophy
Bacterial diseases
Bacterial diseases of the nervous system. Bacterial myositis
Biological and medical sciences
Brain
Cardiac arrhythmia
Case studies
Causes of
Central nervous system
Clinical pathology
Cognitive ability
Complications and side effects
Disease
electromyographic
EMG
Female
Frontal Lobe - pathology
GABA
Hemiplegia
Hospitals
Human bacterial diseases
Humans
Hypertension
Hypoxia
Infectious diseases
Magnetic Resonance Imaging
Medical sciences
Middle Aged
MRI
Ostomy
Parietal Lobe - pathology
Physiological aspects
Short Report
Spinal cord
Tetanus
Tetanus - complications
tetanus toxin
γ-aminobutyric acid
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Description
Summary:A 47 year old woman developed left hemiparesis primarily affecting the lower limbs during the course of severe generalised tetanus. MRI on the 82nd hospital day revealed cortical and subcortical lesions predominantly in the right frontal and parietal lobes in addition to marked brain atrophy. Three months later, the enhancing lesions were still present on follow up MRI. We postulate that structures above brainstem may be involved in severe generalised tetanus.
ISSN:0022-3050
1468-330X
DOI:10.1136/jnnp.74.10.1432