Diffuse brain oedema in idiopathic intracranial hypertension: a quantitative magnetic resonance imaging study

Objectives: To investigate the hypothesis that idiopathic intracranial hypertension is associated with diffuse brain oedema, using quantitative magnetic resonance imaging. Methods: Values for the mean diffusivity of water () and the proton longitudinal relaxation time (T1) were measured for various...

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Bibliographic Details
Published in:Journal of neurology, neurosurgery and psychiatry neurosurgery and psychiatry, 2003-12, Vol.74 (12), p.1693-1696
Main Authors: Bastin, M E, Sinha, S, Farrall, A J, Wardlaw, J M, Whittle, I R
Format: Article
Language:English
Subjects:
ADC
Adolescent
Adult
apparent diffusion coefficient
Biological and medical sciences
Brain
Brain Edema - complications
Brain Edema - pathology
Brain Edema - physiopathology
Cerebral edema
Cerebrospinal fluid. Meninges. Spinal cord
Diagnostic tests
diffusion
Diffusion Magnetic Resonance Imaging
diffusion weighted magnetic resonance imaging
DW-MRI
echo planar
Edema
Ependyma - pathology
Ependyma - physiopathology
Experiments
Female
Humans
Hypertension
Hypotheses
idiopathic intracranial hypertension
IIH
Intracranial hypertension
Intracranial pressure
inversion recovery
inversion time
Magnetic resonance imaging
Medical sciences
Middle Aged
Nervous system (semeiology, syndromes)
Neurology
Patients
proton longitudinal relaxation time
Pseudotumor Cerebri - etiology
Pseudotumor Cerebri - pathology
Pseudotumor Cerebri - physiopathology
region of interest
ROI
Short Report
Citations: Items that cite this one
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Description
Summary:Objectives: To investigate the hypothesis that idiopathic intracranial hypertension is associated with diffuse brain oedema, using quantitative magnetic resonance imaging. Methods: Values for the mean diffusivity of water () and the proton longitudinal relaxation time (T1) were measured for various brain regions in 10 patients with idiopathic intracranial hypertension and 10 age, sex, and weight matched controls. Results: No significant differences in and T1 values were found between patient and control groups in any of the brain regions investigated. Conclusions: The results suggest that idiopathic intracranial hypertension is not associated with abnormalities of convective transependymal water flow leading to diffuse brain oedema.
ISSN:0022-3050
1468-330X
DOI:10.1136/jnnp.74.12.1693