Stress and neuroimmune regulation of gut mucosal function

Besides being the structural support for the epithelium, the lamina propria contains elements important for immunological and absorptive functions. [...]in the lamina propria we find blood and lymph vessels, nerve varicosities, and a plethora of immune cells (plasma cells, lymphocytes, macrophages,...

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Bibliographic Details
Published in:Gut 2000-12, Vol.47 (suppl 4), p.iv49-51
Main Authors: Santos, J, Perdue, M H
Format: Article
Language:English
Subjects:
Animals
Antigens
Corticotropin-Releasing Hormone - physiology
Cytokines
Histamine
Humans
Immunology
Intestinal Mucosa - immunology
Male
Mast Cells - immunology
Mast Cells - physiology
Neuroimmunomodulation - immunology
Neuroimmunomodulation - physiology
Neuropeptides
Permeability
Rats
Rats, Wistar
Rodents
Small intestine
Stem cells
Stress, Physiological - immunology
Stress, Physiological - physiopathology
Studies
Citations: Items that cite this one
Online Access:Get full text
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Description
Summary:Besides being the structural support for the epithelium, the lamina propria contains elements important for immunological and absorptive functions. [...]in the lamina propria we find blood and lymph vessels, nerve varicosities, and a plethora of immune cells (plasma cells, lymphocytes, macrophages, eosinophils, mast cells, dendritic cells, etc). [...]the epithelium plays an active role in immunological and inflammatory events, acting as an antigen presenting system (expressing major histocompatibility antigens), expressing adhesion molecules, and releasing cytokines, chemokines, and other regulatory molecules that participate in the trafficking and homing of immune cells in the gut.
ISSN:0017-5749
1468-3288
1458-3288
DOI:10.1136/gut.47.suppl_4.iv49