A second branched-chain alpha-keto acid dehydrogenase gene cluster (bkdFGH) from Streptomyces avermitilis: its relationship to avermectin biosynthesis and the construction of a bkdF mutant suitable for the production of novel antiparasitic avermectins

• Published in: Journal of Bacteriology 1995-06, Vol.177 (12), p.3504-3511
• Main Authors: Denoya, C D, Fedechko, R W, Hafner, E W, McArthur, H A, Morgenstern, M R, Skinner, D D, Stutzman-Engwall, K, Wax, R G, Wernau, W C
• Format: Article
• Language: English
• Subjects: 3-Methyl-2-Oxobutanoate Dehydrogenase (Lipoamide); Amino Acid Sequence; Anthelmintics - metabolism; Bacteriology; Base Sequence; Cloning, Molecular; Enzymes; Genes; Ivermectin - analogs & derivatives; Ivermectin - metabolism; Ketone Oxidoreductases - genetics; Ketone Oxidoreductases - metabolism; Molecular Sequence Data; Multienzyme Complexes - genetics; Multienzyme Complexes - metabolism; Multigene Family; Phenotype; Sequence Deletion; Sequence Homology, Amino Acid; Streptomyces - enzymology; Streptomyces - genetics; Streptomyces avermitilis
• ISSN: 0021-9193; 1067-8832; 1098-5530
• DOI: 10.1128/jb.177.12.3504-3511.1995

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