Uterine tumour resembling an ovarian sex cord tumour

Endometrial stromal sarcomas account for 0.25% of all uterine malignancies. These tumours were originally divided into low grade and high grade stromal sarcomas, but the recent World Health Organisation classification (2003) recognises low grade stromal sarcoma and undifferentiated endometrial sarco...

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Bibliographic Details
Published in:Journal of clinical pathology 2005-08, Vol.58 (8), p.888-890
Main Authors: Sutak, J, Lazic, D, Cullimore, J E
Format: Article
Language:English
Subjects:
Aged
Biological and medical sciences
Biomarkers, Tumor - metabolism
Case Reports
Endometrial Neoplasms - metabolism
Endometrial Neoplasms - pathology
endometrial stromal sarcoma
Female
Female genital diseases
Gynecology. Andrology. Obstetrics
Humans
Hysterectomy
Investigative techniques, diagnostic techniques (general aspects)
Medical sciences
Neprilysin - metabolism
Ovarian Neoplasms - pathology
Pathology. Cytology. Biochemistry. Spectrometry. Miscellaneous investigative techniques
Sarcoma, Endometrial Stromal - metabolism
Sarcoma, Endometrial Stromal - pathology
sex cord differentiation
Sex Cord-Gonadal Stromal Tumors - metabolism
Sex Cord-Gonadal Stromal Tumors - pathology
Smooth muscle
Tumors
uterine tumour resembling an ovarian sex cord tumour
uterus
UTROSCT
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Summary:Endometrial stromal sarcomas account for 0.25% of all uterine malignancies. These tumours were originally divided into low grade and high grade stromal sarcomas, but the recent World Health Organisation classification (2003) recognises low grade stromal sarcoma and undifferentiated endometrial sarcoma. Low grade sarcomas may exhibit other forms of differentiation, including smooth muscle and sex cord differentiation. In the latter form, the tumour contains epithelial-like or sex cord-like elements often with epithelioid appearance, arranged in nests, cords, trabeculae, solid, or tubular structures. If this element predominates, the tumour is considered to be a uterine tumour resembling ovarian sex cord tumour, and may cause diagnostic difficulties. This case report describes the histological and immunohistochemical features of a uterine stromal sarcoma showing exclusively a pattern reminiscent of ovarian sex cord tumour.
ISSN:0021-9746
1472-4146
DOI:10.1136/jcp.2004.022616