Characteristic clinical features as an aid to the diagnosis of suppurative keratitis caused by filamentous fungi

Aim: To assess whether the presence of characteristic clinical features can be used as a diagnostic aid for suppurative keratitis caused by filamentous fungi. Methods: Patients presenting with suppurative keratitis in India underwent detailed clinical examination followed by microbiological investig...

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Bibliographic Details
Published in:British journal of ophthalmology 2005-12, Vol.89 (12), p.1554-1558
Main Authors: Thomas, P A, Leck, A K, Myatt, M
Format: Article
Language:English
Subjects:
Antibiotics
Biological and medical sciences
Confidence intervals
Datasets
Diagnosis, Differential
Diseases of cornea, anterior segment and sclera
Epidemiologic Methods
Eye Infections, Bacterial - diagnosis
Eye Infections, Bacterial - pathology
Eye Infections, Fungal - diagnosis
Eye Infections, Fungal - pathology
fungal infection
Fungal infections
Fungi
Humans
Keratitis - diagnosis
Keratitis - microbiology
Keratitis - pathology
Laboratories
Medical personnel
Medical sciences
Microscopy
Miscellaneous
Ophthalmology
Studies
suppurative keratitis
Ulcers
World View
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Summary:Aim: To assess whether the presence of characteristic clinical features can be used as a diagnostic aid for suppurative keratitis caused by filamentous fungi. Methods: Patients presenting with suppurative keratitis in India underwent detailed clinical examination followed by microbiological investigation of corneal scrapes. A partial diagnostic score based upon the strength of the association, as estimated by the odds ratio, between reported clinical features and laboratory confirmed diagnoses was devised and subsequently tested using a case series from Ghana. Results: Serrated margins, raised slough, dry texture, satellite lesions and coloration other than yellow occurred more frequently in cases of filamentous fungal keratitis than bacterial keratitis (p
ISSN:0007-1161
1468-2079
DOI:10.1136/bjo.2005.076315