Cushing's disease and craniopharyngioma

A 14-year old girl presented with growth failure and Cushing's disease. Histological examination confirmed a craniopharyngioma but failed to show that the tumour secreted adrenocorticotrophic hormone. We suggest that her Cushing's disease was caused by hypothalamic dysfunction associated w...

Full description

Saved in:
Bibliographic Details
Published in:Archives of disease in childhood 1987-10, Vol.62 (10), p.1077-1078
Main Authors: Ackland, F M, Stanhope, R, Preece, M A
Format: Article
Language:English
Subjects:
Adolescent
Adrenocorticotropic Hormone - metabolism
Biological and medical sciences
Craniopharyngioma - complications
Craniopharyngioma - metabolism
Cushing Syndrome - etiology
Endocrinopathies
Female
Growth Disorders - etiology
Humans
Hypothalamus. Hypophysis. Epiphysis (diseases)
Malignant tumors
Medical sciences
Pituitary Neoplasms - complications
Pituitary Neoplasms - metabolism
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:A 14-year old girl presented with growth failure and Cushing's disease. Histological examination confirmed a craniopharyngioma but failed to show that the tumour secreted adrenocorticotrophic hormone. We suggest that her Cushing's disease was caused by hypothalamic dysfunction associated with increased corticotrophin-releasing hormone secretion, secondary to the craniopharyngioma.
ISSN:0003-9888
1468-2044
DOI:10.1136/adc.62.10.1077