Comparison of FGF1 (aFGF) Expression between the Dorsal Motor Nucleus of Vagus and the Hypoglossal Nucleus of Rat

Neurons in the dorsal motor nucleus of the vagus (DMNV) are more severely affected by axonal injury than most other nerves, such as those of the hypoglossal nucleus. However, the mechanism underlying such a response remains unclear. In this study, we compared the expression of fibroblast growth fact...

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Bibliographic Details
Published in:ACTA HISTOCHEMICA ET CYTOCHEMICA 2006, Vol.39(1), pp.1-7
Main Authors: Toyoda, Ken-ichiro, Okano, Hiroyuki, Bamba, Hitoshi, Hisa, Yasuo, Oomura, Yutaka, Imamura, Toru, Furukawa, Shoei, Tooyama, Ikuo
Format: Article
Language:English
Subjects:
cholinergic neurons
dorsal motor nucleus of vagus
FGF
hypoglossal nucleus
laryngeal nervous system
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Summary:Neurons in the dorsal motor nucleus of the vagus (DMNV) are more severely affected by axonal injury than most other nerves, such as those of the hypoglossal nucleus. However, the mechanism underlying such a response remains unclear. In this study, we compared the expression of fibroblast growth factor 1 (FGF1), a neurotrophic factor, between the DMNV and the hypoglossal nucleus by RT-PCR and immunohistochemical analyses. RT-PCR showed that the level of FGF1 mRNA expression in the DMNV was lower than that in the hypoglossal nucleus (P
ISSN:0044-5991
1347-5800
DOI:10.1267/ahc.05047