Metastatic duodenal GIST: role of surgery combined with imatinib mesylate

The best possible treatment of metastatic high grade large duodenal GIST is controversial. Surgery (with or without segmental organ resection) remains the principal treatment for primary and recurrent GIST. However, patients with advanced duodenal GIST have a high risk of early tumour recurrence and...

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Bibliographic Details
Published in:International seminars in surgical oncology 2007-03, Vol.4 (1), p.9-9, Article 9
Main Authors: Mohiuddin, Kamran, Nizami, Saira, Munir, Asma, Memon, Breda, Memon, Muhammed A
Format: Article
Language:English
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Case Report
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Summary:The best possible treatment of metastatic high grade large duodenal GIST is controversial. Surgery (with or without segmental organ resection) remains the principal treatment for primary and recurrent GIST. However, patients with advanced duodenal GIST have a high risk of early tumour recurrence and short life expectancy. We present a case of a young man treated with a combined modality of surgery and imatinib for an advanced duodenal GIST. He remains asymptomatic and disease free 42 months following this combined approach. Treatment with imatinib has dramatically improved the outlook for patients with advanced, unresectable and/or metastatic disease.
ISSN:1477-7800
1477-7800
DOI:10.1186/1477-7800-4-9