Central sensitisation in visceral pain disorders

The concepts of visceral hyperalgesia and visceral hypersensitivity have been examined in a variety of functional gastrointestinal disorders (FGIDs). Although the pathophysiological mechanisms of pain and hypersensitivity in these disorders are still not well understood, exciting new developments in...

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Bibliographic Details
Published in:Gut 2006-07, Vol.55 (7), p.905-908
Main Authors: Moshiree, B, Zhou, Q, Price, D D, Verne, G N
Format: Article
Language:English
Subjects:
Biological and medical sciences
Brain - physiopathology
central sensitisation
Chronic pain
Enteric Nervous System - physiopathology
FGIDs
fibromyalgia
functional gastrointestinal disorders
Gastroenterology. Liver. Pancreas. Abdomen
Gastroesophageal reflux
Gastrointestinal Diseases - physiopathology
Humans
Hyperalgesia
IBS
Inflammation
Inflammatory Bowel Diseases - physiopathology
Irritable bowel syndrome
Leading
Medical sciences
Nervous system
Neurosciences
Nociceptors - physiology
Pain - physiopathology
Pain Threshold
secondary hyperalgesia
Spinal cord
temporal summation
Trauma
Visceral Afferents - physiology
visceral hypersensitivity
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Summary:The concepts of visceral hyperalgesia and visceral hypersensitivity have been examined in a variety of functional gastrointestinal disorders (FGIDs). Although the pathophysiological mechanisms of pain and hypersensitivity in these disorders are still not well understood, exciting new developments in research have been made in the study of the brain-gut interactions involved in the FGIDs
ISSN:0017-5749
1468-3288
DOI:10.1136/gut.2005.078287