Plasma C reactive protein concentration indicates a direct relation between systemic inflammation and social deprivation

An increase in the plasma concentration of C reactive protein (CRP), within the reference range for the population but below the threshold that indicates clinically significant inflammation, is an independent risk factor for CHD. 3 It is also a predictor for the development of diabetes mellitus 4 -a...

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Bibliographic Details
Published in:Heart (British Cardiac Society) 2006-04, Vol.92 (4), p.533-535
Main Authors: St J O’Reilly, D, Upton, M N, Caslake, M J, Robertson, M, Norrie, J, McConnachie, A, Watt, G C M, Packard, C J
Format: Article
Language:English
Subjects:
Adult
Age
Biological and medical sciences
Biomarkers - blood
BMI
Body mass index
C reactive protein
C-Reactive Protein - metabolism
Cardiology. Vascular system
Cardiovascular disease
Censuses
CHD
Confidence intervals
coronary heart disease
Cross-Sectional Studies
CRP
DEPCAT
deprivation
deprivation score
Enzyme-Linked Immunosorbent Assay
Enzymes
Female
Heart attacks
Humans
Inflammation
Inflammation - blood
Male
Medical sciences
Mens health
Middle Aged
place of residence
Plasma
Population
Proteins
Scientific Letter
Smoking
Social Class
West of Scotland coronary prevention study
Womens health
WOSCOPS
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Summary:An increase in the plasma concentration of C reactive protein (CRP), within the reference range for the population but below the threshold that indicates clinically significant inflammation, is an independent risk factor for CHD. 3 It is also a predictor for the development of diabetes mellitus 4 -a major cause of vascular disease. Full details of the methods used to derive the DEPCATs are available on line from the Medical Research Council's Social and Public Health Sciences Unit at the University of Glasgow ( www.msoc-mrc.gla.ac.uk/Publications/pub/Carstairs_MAIN.html ), which has reported that the DEPCATs of Scottish postcode sectors based on the 2001 census data are strongly correlated (r = 0.955) with those derived from the 1991 census.
ISSN:1355-6037
1468-201X
DOI:10.1136/hrt.2005.063081