High serum level of soluble CD30 in acute primary HIV‐1 infection

CD30 has been suggested to play a role in HIV infection. In this study the serum concentration of soluble CD30 (sCD30) was determined by an ELISA essay on samples collected from patients with acute primary HIV‐1 infection during the acute phase (n = 17) and after seroconversion (n = 13). sCD30 durin...

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Bibliographic Details
Published in:Clinical and experimental immunology 1997-05, Vol.108 (2), p.251-253
Main Authors: PIZZOLO, G., VINANTE, F., NADALI, G., KRAMPERA, M., MOROSATO, L., CHILOSI, M., RAITERI, R., SINICCO, A.
Format: Article
Language:English
Subjects:
Acute Disease
acute HIV‐1 infection
Adult
AIDS/HIV
Biological and medical sciences
CD30
Female
HIV Antigens - blood
HIV Infections - blood
HIV Infections - immunology
HIV Infections - virology
HIV-1 - immunology
human immunodeficiency virus 1
Humans
Immunodeficiencies
Immunodeficiencies. Immunoglobulinopathies
Immunopathology
Ki-1 Antigen - blood
Male
Medical sciences
Middle Aged
Original
Solubility
soluble CD30
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Summary:CD30 has been suggested to play a role in HIV infection. In this study the serum concentration of soluble CD30 (sCD30) was determined by an ELISA essay on samples collected from patients with acute primary HIV‐1 infection during the acute phase (n = 17) and after seroconversion (n = 13). sCD30 during acute infection was consistently elevated (137.58 ± 120.33 versus 6.4 ± 5.4 U/ml (mean ± s.d.) in normal controls; P 
ISSN:0009-9104
1365-2249
DOI:10.1046/j.1365-2249.1997.d01-1005.x