Maturational changes in dentin mineral properties

• Published in: Bone (New York, N.Y.) N.Y.), 2007-05, Vol.40 (5), p.1399-1407
• Main Authors: Verdelis, K, Lukashova, L, Wright, J.T, Mendelsohn, R, Peterson, M.G.E, Doty, S, Boskey, A.L
• Format: Article
• Language: English
• Subjects: Animals; Biological and medical sciences; Carbonates - metabolism; Cattle; Dentin; Dentin - metabolism; Female; Fourier Transform Infrared spectroscopy; Fundamental and applied biological sciences. Psychology; Imaging; Maturation; Mineral; Minerals - metabolism; Orthopedics; Spectrum Analysis; Vertebrates: anatomy and physiology, studies on body, several organs or systems
• ISSN: 8756-3282; 1873-2763
• DOI: 10.1016/j.bone.2006.12.061

Abstract In this study the changes in properties of the maturing mantle and circumpulpal dentin were quantitatively analyzed. Sections from six fetal bovine undecalcified incisors were used. Regions of mantle and circumpulpal dentin of sequential maturation stages were identified on spectroscopic images acquired by Fourier Transform Infrared Imaging. Spectroscopic parameters corresponding to mineral properties at these stages were analyzed and reported as a function of distance from the cervix of the incisor, the latter representing tissue age. Mineral parameters were correlated with distance from the cervix. Values of these parameters in mantle and circumpulpal dentin were compared. A multi-phasic pattern of changes was found for all the parameters examined, with most of the alterations occurring in the initial maturation period. The patterns of temporal variation in mantle and circumpulpal dentin mineral properties show distinct developmental stages and were not identical for the two dentin compartments. The study showed that mineral maturation in dentin is not a linear process and that mantle dentin is developmentally distinct from circumpulpal dentin, presenting at certain stages different physicochemical events during the maturation of the tissue.