THERAPEUTIC AGENTS IN ACNE VULGARIS. I. TETRACYCLINE

A total of 120 consecutive patients with pustular and cystic acne vulgaris were selected for study. Patients were assigned a placebo and a tetracycline medication in a random method. Of the 53 patients who were given tetracycline, 45 showed some response, which was fair in 19 and excellent in 26. Of...

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Bibliographic Details
Published in:Canadian Medical Association journal 1963-11, Vol.89 (21), p.1096-1097
Main Authors: STEWART, W D, MADDIN, S, NELSON, A J, DANTO, J L
Format: Article
Language:English
Subjects:
Acne Vulgaris
Anti-Bacterial Agents
Canada
Female
Humans
Male
Old Medline
Probability
Short Communication
Tetracycline
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Summary:A total of 120 consecutive patients with pustular and cystic acne vulgaris were selected for study. Patients were assigned a placebo and a tetracycline medication in a random method. Of the 53 patients who were given tetracycline, 45 showed some response, which was fair in 19 and excellent in 26. Of the 55 patients who received placebo, 24 showed no response while 31 showed some improvement. No side effects were reported. The difference in response between the two groups is statistically significant. It is concluded that administration of 250 mg. tetracycline four times daily, even for periods as short as two weeks, enhances the likelihood of improvement of cystic or pustular acne vulgaris.
ISSN:0008-4409