Incidence of and Factors Associated with Achieving Target Lipid Levels in Patients with Peripheral Arterial Disease

BACKGROUND: Patients with peripheral arterial disease (PAD) have increased mortality compared with patients without PAD. Coronary artery disease (CAD) accounts for almost 75% of deaths in PAD patients. Studies suggest that PAD is underdiagnosed and atherosclerotic risk factors undertreated when comp...

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Bibliographic Details
Published in:Journal of general internal medicine : JGIM 2006-07, Vol.21 (7), p.711-714
Main Authors: Banta, Meggan R., Ma, Fangchao, Bravata, Dawn M., Kirsner, Robert S., Federman, Daniel G.
Format: Article
Language:English
Subjects:
Aged
Analysis of Variance
Arterial Occlusive Diseases - blood
Biological and medical sciences
Blood and lymphatic vessels
Cardiology. Vascular system
Cardiovascular disease
Cholesterol, LDL - blood
coronary artery disease
Diseases of the peripheral vessels. Diseases of the vena cava. Miscellaneous
Florida
General aspects
Humans
hyperlipidemia
Hypolipidemic Agents - therapeutic use
Internal medicine
Lipids - blood
Medical sciences
Middle Aged
Miscellaneous
Mortality
Multivariate Analysis
Original
Patient Compliance
peripheral arterial disease
Public health. Hygiene
Public health. Hygiene-occupational medicine
Regression Analysis
Retrospective Studies
Treatment Outcome
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Summary:BACKGROUND: Patients with peripheral arterial disease (PAD) have increased mortality compared with patients without PAD. Coronary artery disease (CAD) accounts for almost 75% of deaths in PAD patients. Studies suggest that PAD is underdiagnosed and atherosclerotic risk factors undertreated when compared with CAD. OBJECTIVE: To determine whether cholesterol guidelines are being met in patients with PAD and to determine whether any independent factors increase the likelihood of reaching goal low‐density lipoprotein (LDL). DESIGN: A retrospective chart review of subjects diagnosed with PAD in 2001 at 2 Veterans Affairs Medical Centers. MEASUREMENTS: Univariate analysis compares baseline characteristics between those reaching goal and those who do not. Multivariate logistic regression analysis identified predictors of meeting LDL goal among PAD patients. RESULTS: Of 315 patients, 62% reached goal LDL. Those more likely to reach goal were older, had hypertension, and a history of CAD and stroke. Positive predictors of LDL goal were age and CAD, while smoking was a negative predictor. CONCLUSION: The majority of veterans with PAD received lipid‐lowering medication and achieve goal LDL, but they are more likely to do so if they are older than 70 and have a history of CAD.
ISSN:0884-8734
1525-1497
DOI:10.1111/j.1525-1497.2006.00456.x